SHFL Antibodies

AND SHFL ELISA kits, SHFL Proteins

Many biological assays use antibodies to detect SHFL, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SHFL in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SHFL antibodies...

We validate the specificity of these antibodies to SHFL by testing them on tissues known to express SHFL positively and negatively. Browse below to find the SHFL antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SHFL Infographic by Boster Bio

All SHFL Products

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SHFL (NM_018381) Human Recombinant Protein

Coomassie blue staining of purified SHFL protein

$1249
Cat # PROTQ9NUL5
20 µg

SHFL (NM_018381) Human Over-expression Lysate

Human

$628
Cat # LS055337
20 µg, 100 µg

SHFL Overview

Facts about Shiftless antiviral inhibitor of ribosomal frameshifting protein.

SHFL 3D structure. Source: alphafold

Shiftless antiviral inhibitor of ribosomal frameshifting protein (SHFL)

Exhibits antiviral activity against dengue virus (DENV) and can inhibit the replication of all DENV serotypes. May block the protein translation of DENV RNA through its association with mobile mRNA-binding proteins and viral RNA.

Can also limit the replication of hepatitis C virus (HCV), West Nile virus (WNV), Chikungunya virus (CHIKV), herpes simplex virus type 1 (HHV-1) and human adenovirus (PubMed:26735137). .

Gene Information

Human
Gene Name:	SHFL
Uniprot:	Q9NUL5
Entrez:	55337

Family

Belongs to:

SHFL family

Alternative Names

Shiftless antiviral inhibitor of ribosomal frameshifting protein

Molecular Weight

Mass (kDA):
33.11 kDA

Genomic Context


Human

Location:	19p13.2
Sequence:	19; NC_000019.10 (10086119..10093249)

Subcellular Localizations

Cytoplasm. Nucleus. Cytoplasm, P-body. Predominantly found in the cytoplasm (PubMed:26735137). After infection, relocalizes to the DENV replication complex in perinuclear regions (PubMed:27974568).

Interacting Proteins

DRICH1
DTNBP1
IKZF1
KRT40
KRTAP10-5

KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP2-3
KRTAP4-12

KRTAP4-2
KRTAP5-9
KRTAP9-2
LZTS2
MAGEA1

MDFI
MEOX2
MTUS2
NOTCH2NL
PDE4DIP

SPRY2
SSX2IP
TCF4
TERF1
TNS2

TRAF1

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SHFL

References

PMID: 26735137 by Suzuki Y., et al. Characterization of RyDEN (C19orf66) as an interferon-stimulated cellular inhibitor against dengue virus replication.

PMID: 27974568 by Balinsky C.A., et al. IRAV (FLJ11286), an Interferon-Stimulated Gene with Antiviral Activity against Dengue Virus, Interacts with MOV10.