SH3KBP1-binding protein 1 Antibodies

AND SHKBP1 ELISA kits, SH3KBP1-binding protein 1 Proteins

Many biological assays use antibodies to detect SH3KBP1-binding protein 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SH3KBP1-binding protein 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SH3KBP1-binding protein 1 antibodies...

We validate the specificity of these antibodies to SH3KBP1-binding protein 1 by testing them on tissues known to express SHKBP1 positively and negatively. Browse below to find the SHKBP1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SHKBP1 Infographic by Boster Bio

All SHKBP1 Products

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Anti-SHKBP1 Antibody Picoband®

Western blot analysis of SHKBP1 using anti-SHKBP1 antibody (A14104-1)

IHC analysis of SHKBP1 using anti-SHKBP1 antibody (A14104-1)

Human

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A14104-1
100 µg/vial

SHKBP1 (NM_138392) Human Over-expression Lysate

Human

$628
Cat # LS092799
20 µg, 100 µg

SHKBP1 Overview

Facts about SH3KBP1-binding protein 1.

SHKBP1 3D structure. Source: alphafold

SH3KBP1-binding protein 1 (SHKBP1)

Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.

Gene Information

Human
Gene Name:	SHKBP1
Uniprot:	Q8TBC3
Entrez:	92799

Family

Belongs to:

KCTD3 family

Alternative Names

PP203; Sb1; SH3KBP1 binding protein 1; SH3KBP1-binding protein 1

Molecular Weight

Mass (kDA):
76.344 kDA

Genomic Context


Human

Location:	19q13.2
Sequence:	19; NC_000019.10 (40576864..40591399)

Tissue Specificity

Widely expressed.

Subcellular Localizations

Lysosome.

Diseases

Neoplasms
Cholangiocarcinoma
Infarction
Melanoma
Malignant Neoplasm Of Breast
Malignant Paraganglionic Neoplasm
Kidney Neoplasm
Leukemia, Myelocytic, Acute
Myocardial Infarction

Malignant Neoplasms
Myeloid Leukemia
Leukemia
Inflammation

Interacting Proteins

CUL3

Pathways

Endocytosis

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SHKBP1

References

PMID: 16733801 by Liu J.P., et al. Human homologue of SETA binding protein 1 interacts with cathepsin B and participates in TNF-Induced apoptosis in ovarian cancer cells.

PMID: 28963344 by Pinkas D.M., et al. Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases.