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SIAH3 Antibodies

AND SIAH3 ELISA kits, SIAH3 Proteins

Many biological assays use antibodies to detect SIAH3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SIAH3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SIAH3 antibodies...

We validate the specificity of these antibodies to SIAH3 by testing them on tissues known to express SIAH3 positively and negatively. Browse below to find the SIAH3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SIAH3 Infographic by Boster Bio

SIAH3 protein infographic

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SIAH3 (NM_198849) Human Over-expression Lysate

SIAH3 Human Over-expression Lysates NM_198849

SIAH3 Human Over-expression Lysates NM_198849

Human

$628
Cat # LS283514
20 µg, 100 µg

SIAH3 Overview

Facts about Seven in absentia homolog 3.

SIAH3 3D structure

SIAH3 3D structure. Source: alphafold

Seven in absentia homolog 3 (SIAH3)

Negative regulator of PRKN translocation to damaged mitochondria. Acts likely by destabilizing PINK1 protein, hence inhibiting PRKN targeting to dysfunctional depolarized mitochondria.

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Gene Information

Human
Gene Name:	SIAH3
Uniprot:	Q8IW03
Entrez:	283514

Gene Information

Family

Belongs to:

SINA (Seven in absentia) family

Family

Alternative Names

Seven In Absentia Homolog 3 (Drosophila); Seven In Absentia Homolog 3; Siah E3 Ubiquitin Protein Ligase Family Member 3; siah-3

Molecular Weight

Mass (kDA):
30.66 kDA

Molecular Weight

Genomic Context


Human

Location:	13q14.13
Sequence:	13; NC_000013.11 (45777242..45851753, complement)

Subcellular Localizations

Mitochondrion.

Subcellular Localization

Diseases

Malignant Neoplasm Of Prostate
Neoplasm Metastasis
Malignant Neoplasms
Prostatic Neoplasms
Neoplasms

Disease

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For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SIAH3

References

PMID: 24270810 by Hasson S.A., et al. High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.