SIGLEC16 Antibodies

AND SIGLEC16 ELISA kits, SIGLEC16 Proteins

Many biological assays use antibodies to detect SIGLEC16, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SIGLEC16 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SIGLEC16 antibodies...

We validate the specificity of these antibodies to SIGLEC16 by testing them on tissues known to express SIGLEC16 positively and negatively. Browse below to find the SIGLEC16 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SIGLEC16 Infographic by Boster Bio

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SIGLEC16 Overview

Facts about Sialic acid-binding Ig-like lectin 16.

SIGLEC16 3D structure. Source: alphafold

Sialic acid-binding Ig-like lectin 16 (SIGLEC16)

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. .

Gene Information

Human
Gene Name:	SIGLEC16
Uniprot:	A6NMB1
Entrez:	400709

Family

Belongs to:

immunoglobulin superfamily

Alternative Names

Sialic acid-binding Ig-like lectin 16

Molecular Weight

Mass (kDA):
52.992 kDA

Genomic Context


Human

Location:	19q13.33
Sequence:	19; NC_000019.10 (49969664..49975814)

Tissue Specificity

Expressed in bone marrow, fetal brain, fetal liver, lung and salivary gland. Detected in brain, macrophage, cancerous esophagus and lung at protein level.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SIGLEC16

References

PMID: 11986327 by Angata T., et al. Cloning and characterization of human Siglec-11. A recently evolved signaling molecule that can interact with SHP-1 and SHP-2 and is expressed by tissue macrophages, including brain microglia.

PMID: 18629938 by Cao H., et al. SIGLEC16 encodes a DAP12-associated receptor expressed in macrophages that evolved from its inhibitory counterpart SIGLEC11 and has functional and non-functional alleles in humans.