SIL1 Antibodies

AND SIL1 ELISA kits, SIL1 Proteins

Many biological assays use antibodies to detect SIL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SIL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SIL1 antibodies...

We validate the specificity of these antibodies to SIL1 by testing them on tissues known to express SIL1 positively and negatively. Browse below to find the SIL1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SIL1 Infographic by Boster Bio

All SIL1 Products

Product

Figures

Specificity

Applications

Price

SIL1 (NM_001037633) Human Recombinant Protein

$1249
Cat # PROTQ9H173
20 µg

Anti-SIL1 Mouse Monoclonal Antibody [Clone ID: OTI3B11]

Human, Mouse, Rat

Flow Cytometry, IF, IHC, WB

$523
Cat # M04766
100 µl

Anti-SIL1 Mouse Monoclonal Antibody [Clone ID: OTI1F9]

+12

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M04766-1
100 µl

SIL1 (NM_001037633) Human Over-expression Lysate

Human

$628
Cat # LS064374
100 µg

SIL1 Overview

Facts about Nucleotide exchange factor SIL1.

SIL1 3D structure. Source: alphafold

Nucleotide exchange factor SIL1 (SIL1)

Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5.

Gene Information

Human
Gene Name:	SIL1
Uniprot:	Q9H173
Entrez:	64374

Family

Belongs to:

SIL1 family

Alternative Names

BAPMarinesco-Sjogren syndrome; BiP-associated protein; MSS; nucleotide exchange factor SIL1; SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae); ULG5

Molecular Weight

Mass (kDA):
52.085 kDA

Genomic Context


Human

Location:	5q31.2
Sequence:	5; NC_000005.10 (138946724..139198368, complement)

Tissue Specificity

Highly expressed in tissues which produce large amounts of secreted proteins such as kidney, liver and placenta. Also expressed in colon, heart, lung, ovary, pancreas, peripheral leukocyte, prostate, spleen and thymus. Expressed at low levels throughout the brain.

Subcellular Localizations

Endoplasmic reticulum lumen.

Diseases

Marinesco-sjogren Syndrome
Spinocerebellar Degeneration
Ataxia
Cerebellar Ataxia
Myopathy
Atrophy
Nerve Degeneration
Multisystem Disorder
Cataract
Dizziness
Ophthalmoplegia

Liver Diseases
Neurodegenerative Disorders
Polycystic Liver Disease
Optic Atrophy
Genital Neoplasms, Female
Genital Neoplasms, Male

Interacting Proteins

UBQLN1

Pathways

Transport
Dna Methylation
Methylation
Protein Folding
Gene Silencing
Histone Modification
Protein Transport
Localization
Pathogenesis
Rna Interference
Chromatin Remodeling

Secretion
Glycosylation
Neuron Death
Germination
Seedling Development

PTMs

Methylation

Farnesylation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SIL1

References

PMID: 11101517 by Tyson J.R., et al. LHS1 and SIL1 provide a lumenal function that is essential for protein translocation into the endoplasmic reticulum.

PMID: 12356756 by Chung K.T., et al. BAP, a mammalian BiP-associated protein, is a nucleotide exchange factor that regulates the ATPase activity of BiP.