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SLAM family member 6 Antibodies
AND Slamf6 ELISA kits, SLAM family member 6 Proteins
Many biological assays use antibodies to detect SLAM family member 6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLAM family member 6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLAM family member 6 antibodies...
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Slamf6 Infographic by Boster Bio
All Slamf6 Products
Product
Figures
Specificity
Applications
Price
Cynomolgus monkey, Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M05310
100 μg
Cat # M05310
100 μg
Slamf6 Overview
Facts about SLAM family member 6.
SLAM family member 6 (Slamf6)
Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune reaction.
Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2 (PubMed:19648922). Triggers cytolytic action only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors (By similarity).
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Slamf6 |
| Uniprot: | Q9ET39 |
| Entrez: | 30925 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Activating NK receptor; CD352 antigen; CD352; KALIFLJ50657; Ly108; NK-T-B-antigen; NTBA receptor; NTBA; NTB-A; NTB-AMGC104953; NTBAT- and B-cell antigen; SF2000; SLAM family member 6; SLAMF6
Molecular Weight
Mass (kDA):
38.638 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 1 H3|1 79.54 cM |
| Sequence: | 1; |
Tissue Specificity
Expressed on hematopoietic cells. Isoform 3 is expressed in thymocytes and B lymphocytes of C57Bl/6 strain.
Diseases
- Lupus Erythematosus, Systemic
- Tissue Adhesions
- Immunologic Deficiency Syndromes
- Malignant Neoplasms
- Autoimmune Reaction
- Neoplasms
- Autoimmunity
- Cell Transformation, Neoplastic
- Radiation Chimera Disorder
- Genetic Diseases, X-linked
- Lung Diseases
- Autoimmune Diseases
Pathways
- Cell Development
- Cell Adhesion
- Lymphocyte Activation
- Germinal Center Formation
- Cell Activation
- Immune System Process
- Multi-organism Process
- T Cell Activation
- Immune Response
- Leukocyte Differentiation
- Humoral Immune Response
- Defense Response
PTMs
- Disulfide bond
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Slamf6
bosterbio.com/bosterbio-gene-info-cards/Slamf6
References
PMID: 11132158 by Peck S.R., et al. Ly108: a new member of the mouse CD2 family of cell surface proteins.
PMID: 21422172 by Keszei M., et al. A novel isoform of the Ly108 gene ameliorates murine lupus.