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- Table of Contents

Facts about Zinc finger and BTB domain-containing protein 18.
Also involved in controlling cell division of progenitor cells and regulating the survival of postmitotic cortical neurons. Specifically binds the consensus DNA sequence 5'- [AC]ACATCTG[GT][AC]-3' that contains the E box center, and functions by recruiting chromatin remodeling multiprotein complexes.
| Human | |
|---|---|
| Gene Name: | ZBTB18 |
| Uniprot: | Q99592 |
| Entrez: | 10472 |

| Belongs to: |
|---|
| krueppel C2H2-type zinc-finger protein family |

Zinc finger and BTB domain-containing protein 18
Mass (kDA):
58.354 kDA

| Human | |
|---|---|
| Location: | 1q44 |
| Sequence: | 1; NC_000001.11 (244048939..244057476) |
Lymphoid tissues, testis, heart, brain, skeletal muscle, and pancreas and, at much lower level, other tissues.
Nucleus. Associates with condensed chromatin.


PMID: 7633419 by Becker K.G., et al. Rapid isolation and characterization of 118 novel C2H2-type zinc finger cDNAs expressed in human brain.
PMID: 9756912 by Aoki K., et al. RP58 associates with condensed chromatin and mediates a sequence- specific transcriptional repression.