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- Table of Contents
SLC12A2 Antibodies
AND SLC12A2 ELISA kits, SLC12A2 Proteins
Many biological assays use antibodies to detect SLC12A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC12A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC12A2 antibodies...
Designing a Western blot for SLC12A2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SLC12A2 Western Blot GuideSLC12A2 Infographic by Boster Bio
All SLC12A2 Products
Product
Figures
Specificity
Applications
Price
Anti-NKCC1/SLC12A2 Antibody Picoband®
2 Citations
Human, Mouse, Rat
IF, IHC, WB
$370
Cat # PA2169
100 μg/vial
Cat # PA2169
100 μg/vial
Human, Mouse, Rat
IF, IHC, WB
$370
Cat # M03603
100 μg/vial
Cat # M03603
100 μg/vial
Human, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A03603
100 μg/vial
Cat # A03603
100 μg/vial
SLC12A2 Overview
Facts about Solute carrier family 12 member 2.
Solute carrier family 12 member 2 (SLC12A2)
Electrically silent transporter system. Mediates sodium and chloride reabsorption.
Plays a vital role in the regulation of ionic balance and cell volume. .
Gene Information
| Human | |
|---|---|
| Gene Name: | SLC12A2 |
| Uniprot: | P55011 |
| Entrez: | 6558 |
Family
| Belongs to: |
|---|
| SLC12A transporter family |
Alternative Names
Basolateral Na-K-Cl symporter; BSC; BSC2; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1; NKCC1; NKCC1MGC104233; SLC12A2; solute carrier family 12 (sodium/potassium/chloride transporters), member 2; solute carrier family 12 member 2
Molecular Weight
Mass (kDA):
131.447 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q23.3 |
| Sequence: | 5; NC_000005.10 (128083766..128189677) |
Tissue Specificity
Expressed in many tissues.
Subcellular Localizations
Membrane; Multi-pass membrane protein.
Diseases
- Complete Hearing Loss
- Nervousness
- Bartter Disease
- Dysequilibrium Syndrome
- Deafness Congenital
- Schizophrenia
- Hypertensive Disease
- Limb Deformities, Congenital
- Disease Of Adrenal Medulla
- Metabolic Alkalosis
- Malignant Neoplasm Of Breast
- Infertility
Interacting Proteins
- EZR
- OXSR1
Pathways
- Transport
- Secretion
- Insulin Secretion
- Ion Transport
- Response To Water Deprivation
- Electron Transport
- Brain Development
- Fertilization
- Immune Response
- Pigmentation
- Inner Ear Development
- Spermatogenesis
- Embryo Development
PTMs
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC12A2
bosterbio.com/bosterbio-gene-info-cards/SLC12A2
References
PMID: 7629105 by Payne J.A., et al. Primary structure, functional expression, and chromosomal localization of the bumetanide-sensitive Na-K-Cl cotransporter in human colon.
PMID: 11700976 by Vibat C.R., et al. Quantitation of Na(+)-K(+)-2Cl(-) cotransport splice variants in human tissues using kinetic polymerase chain reaction.