SLC1A4 Antibodies

AND SLC1A4 ELISA kits, SLC1A4 Proteins

Many biological assays use antibodies to detect SLC1A4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC1A4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC1A4 antibodies...

We validate the specificity of these antibodies to SLC1A4 by testing them on tissues known to express SLC1A4 positively and negatively. Browse below to find the SLC1A4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC1A4 Infographic by Boster Bio

All SLC1A4 Products

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Anti-SLC1A4 Antibody Picoband®

3 Q&As

Anti-SLC1A4 antibody, PA2186, Western blottingLane 1: U87 Cell LysateLane 2: Rat Brain Tissue LysateLane 3: Mouse Brain Tissue Lysate

Anti-SLC1A4 antibody, PA2186, IHC(P)IHC(P): Human Intestinal Cancer Tissue

Human, Mouse, Rat

IHC, WB

$370
Cat # PA2186
100 μg/vial

SLC1A4 (NM_003038) Human Over-expression Lysate

Human

$628
Cat # LS006509
20 µg, 100 µg

SLC1A4 Overview

Facts about Neutral amino acid transporter A.

SLC1A4 3D structure. Source: alphafold

Neutral amino acid transporter A (SLC1A4)

Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence.

Gene Information

Human
Gene Name:	SLC1A4
Uniprot:	P43007
Entrez:	6509

Family

Belongs to:

dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family

Alternative Names

Alanine/serine/cysteine/threonine transporter 1; ASCT1 ASCT-1; ASCT1; neutral amino acid transporter A; SATTglutamate/neutral amino acid transporter; solute carrier family 1 (glutamate/neutral amino acid transporter), member 4; Solute carrier family 1 member 4

Molecular Weight

Mass (kDA):
55.723 kDA

Genomic Context


Human

Location:	2p14
Sequence:	2; NC_000002.12 (64988479..65023865)

Tissue Specificity

Expressed mostly in brain, muscle, and pancreas but detected in all tissues examined.

Subcellular Localizations

Membrane; Multi-pass membrane protein. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Diseases

Schizophrenia
Sclerosis
Neoplasms
Ischemia
Inflammation
Nervousness
Bipolar Disorder
Nerve Degeneration
Disease Of Adrenal Medulla
Metaplasia
Brain Ischemia
Primary Lateral Sclerosis

Glioma
Hypoxia
Amyotrophic Lateral Sclerosis
Endoplasmic Reticulum Stress
Immunologic Deficiency Syndromes
Dysplasia
Esophageal Neoplasms

Pathways

Transport
Localization
Pathogenesis
Glycosylation
Translation
Amino Acid Transport
Cell Proliferation
Glutamine Transport
Glutamate Homeostasis
Leucine Transport
Syncytium Formation

Proline Transport
Reverse Transcription
Protein N-linked Glycosylation
Cellular Localization
Response To Leucine
Secretion

PTMs

Phosphorylation
Carboxylation

Hydroxylation
Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC1A4

References

PMID: 8101838 by Arriza J.L., et al. Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family.

PMID: 8340364 by Shafqat S., et al. Cloning and expression of a novel Na(+)-dependent neutral amino acid transporter structurally related to mammalian Na+/glutamate cotransporters.