Sodium/potassium/calcium exchanger 1 (SLC24A1)

Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of the retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion through this protein that plays a key role in the process of light adaptation.

Transports 1 Ca(2+) and one K(+) in exchange for 4 Na(+). .