Mitoferrin-2 Antibodies

AND SLC25A28 ELISA kits, Mitoferrin-2 Proteins

Many biological assays use antibodies to detect Mitoferrin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Mitoferrin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Mitoferrin-2 antibodies...

We validate the specificity of these antibodies to Mitoferrin-2 by testing them on tissues known to express SLC25A28 positively and negatively. Browse below to find the SLC25A28 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC25A28 Infographic by Boster Bio

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SLC25A28 (NM_031212) Human Over-expression Lysate

Human

$628
Cat # LS081894
20 µg, 100 µg

SLC25A28 Overview

Facts about Mitoferrin-2.

SLC25A28 3D structure. Source: alphafold

Mitoferrin-2 (SLC25A28)

Mitochondrial iron transporter which mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly in non-erythroid cells.

The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme (By similarity). .

Gene Information

Human
Gene Name:	SLC25A28
Uniprot:	Q96A46
Entrez:	81894

Family

Belongs to:

mitochondrial carrier (TC 2.A.29) family

Alternative Names

DKFZp547C109; hMRS3/4; MFRN2; Mitochondrial iron transporter 2; Mitochondrial RNA-splicing protein 3/4 homolog; mitoferrin-2; MRS3/4MRS4Lmitochondrial RNA splicing protein 3/4; NPD016; putative mitochondrial solute carrier; Solute carrier family 25 member 28; solute carrier family 25, member 28

Molecular Weight

Mass (kDA):
39.272 kDA

Genomic Context


Human

Location:	10q24.2
Sequence:	10; NC_000010.11 (99610522..99659507, complement)

Tissue Specificity

Ubiquitous. Expressed in placenta, lung, kidney, pancreas, liver, brain, skeletal muscle and heart.

Subcellular Localizations

Mitochondrion inner membrane; Multi-pass membrane protein. Isoform 1 and isoform 2 are both localized in the mitochondrion.

Diseases

Malignant Catarrhal Fever
Malignant Neoplasms
Anemia
Chronic Progressive External Ophthalmoplegia
Hypochromic Anemia
Neoplasms
Uterine Cervical Neoplasm

Ataxia, Spinocerebellar

Pathways

Rna Splicing
Tissue Development
Heart Development
Rna Interference
Localization

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC25A28

References

PMID: 11297739 by Li F.-Y., et al. Characterization of a novel human putative mitochondrial transporter homologous to the yeast mitochondrial RNA splicing proteins 3 and 4.