Pendrin Antibodies

AND SLC26A4 ELISA kits, Pendrin Proteins

Many biological assays use antibodies to detect Pendrin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pendrin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pendrin antibodies...

We validate the specificity of these antibodies to Pendrin by testing them on tissues known to express SLC26A4 positively and negatively. Browse below to find the SLC26A4 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Pendrin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the SLC26A4 Western Blot Guide

SLC26A4 Infographic by Boster Bio

All SLC26A4 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SLC26A4 Antibody Picoband®

Western blot analysis of SLC26A4 using anti-SLC26A4 antibody (A00919-1)

Human, Mouse, Rat

$370
Cat # A00919-1
100 μg/vial

SLC26A4 (NM_000441) Human Over-expression Lysate

Human

$960
Cat # LS005172
20 µg, 100 µg

SLC26A4 (NM_000441) Human Recombinant Protein

Coomassie blue staining of purified SLC26A4 protein

$1249
Cat # PROTO43511
20 µg

SLC26A4 Overview

Facts about Pendrin.

SLC26A4 3D structure. Source: alphafold

Pendrin (SLC26A4)

Sodium-independent transporter of chloride and iodide. .

Gene Information

Human
Gene Name:	SLC26A4
Uniprot:	O43511
Entrez:	5172

Family

Belongs to:

SLC26A/SulP transporter (TC 2.A.53) family

Alternative Names

DFNB4; EVA; PDSTDH2B; pendrin; Sodium-independent chloride/iodide transporter; Solute carrier family 26 member 4; solute carrier family 26, member 4

Molecular Weight

Mass (kDA):
85.723 kDA

Genomic Context


Human

Location:	7q22.3
Sequence:	7; NC_000007.14 (107660828..107717809)

Tissue Specificity

High expression in adult thyroid, lower expression in adult and fetal kidney and fetal brain. Not expressed in other tissues.

Subcellular Localizations

Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Localizes to the apical brush border of cells in the cortical collecting ducts of the kidney.

Diseases

Complete Hearing Loss
Pendred's Syndrome
Sensorineural Hearing Loss (disorder)
Goiter
Hypothyroidism
Deafness Congenital
Nodular Goiter
Dysplasia
Thyroid Neoplasm
Adenoma
Carcinoma
Neoplasms

Malignant Neoplasms
Thyroid Diseases
Hypertensive Disease
Congenital Ear Anomaly Nos (disorder)
Acidosis
Alkalosis
Hereditary Diseases

Pathways

Transport
Secretion
Localization
Pathogenesis
Excretion
Iodide Transport
Sulfate Transport
Ion Transport
Anion Transport
Ear Development
Inner Ear Development
Chloride Transport
Glycosylation

Methylation
Regulation Of Blood Pressure
Cell Proliferation
Acid Secretion
Translation
Fluid Transport
Cell Growth

PTMs

Methylation
Phosphorylation
Iodination
Glycosylation

Nitration
Biotinylation
Reduction
Deacetylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC26A4

References

PMID: 9398842 by Everett L.A., et al. Pendred syndrome is caused by mutations in a putative sulphate transporter gene (PDS).

PMID: 10192399 by Scott D.A., et al. The Pendred syndrome gene encodes a chloride-iodide transport protein.