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- Table of Contents
SLC2A8 Antibodies
AND SLC2A8 ELISA kits, SLC2A8 Proteins
Many biological assays use antibodies to detect SLC2A8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC2A8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC2A8 antibodies...
Designing a Western blot for SLC2A8? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SLC2A8 Western Blot GuideDesigning an IHC experiment for SLC2A8? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SLC2A8 IHC GuideSLC2A8 Infographic by Boster Bio
All SLC2A8 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB
$370
Cat # PA2165
100 μg/vial
Cat # PA2165
100 μg/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M06641-1
100 μg
Cat # M06641-1
100 μg
SLC2A8 Overview
Facts about Solute carrier family 2, facilitated glucose transporter member 8.
Solute carrier family 2, facilitated glucose transporter member 8 (SLC2A8)
Insulin-regulated facilitative glucose transporter. Binds cytochalasin B at a glucose-inhibitable method.
Seems like a dual-specific sugar transporter because it is inhibitable by fructose (By similarity). .
Gene Information
| Human | |
|---|---|
| Gene Name: | SLC2A8 |
| Uniprot: | Q9NY64 |
| Entrez: | 29988 |
Family
| Belongs to: |
|---|
| major facilitator superfamily |
Alternative Names
GLUT-8; GLUT8solute carrier family 2 (facilitated glucose transporter) member 8; GLUTX1facilitated glucose transporter member 8; solute carrier family 2 (facilitated glucose transporter), member 8
Molecular Weight
Mass (kDA):
50.819 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q33.3 |
| Sequence: | 9; NC_000009.12 (127397138..127407898) |
Tissue Specificity
Highly expressed in testis, but not in testicular carcinoma. Lower amounts present in most other tissues.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration.
Diseases
- Diabetes Mellitus
- Diabetes Mellitus, Experimental
- Diabetes Mellitus, Insulin-dependent
- Nervousness
- Malignant Neoplasms
- Neoplasms
- Diabetes Mellitus, Non-insulin-dependent
- Hypoxia
- Carcinoma
- Endometrial Polyp
- Polycystic Ovary Syndrome
- Hyperglycemia
Pathways
- Transport
- Localization
- Glucose Transport
- Glucose Homeostasis
- Spermatogenesis
- Fertilization
- Endocytosis
- Decidualization
- Cellular Localization
- Embryo Development
- Mating
- Glycosylation
- Sperm Motility
PTMs
- Glycosylation
- Carboxylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC2A8
bosterbio.com/bosterbio-gene-info-cards/SLC2A8
References
PMID: 10821868 by Doege H., et al. GLUT8, a novel member of the sugar transport facilitator family with glucose transport activity.
PMID: 10671487 by Ibberson M.R., et al. GLUTX1, a novel mammalian glucose transporter expressed in the central nervous system and insulin-sensitive tissues.