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SLC3A1 Antibodies
AND SLC3A1 ELISA kits, SLC3A1 Proteins
Many biological assays use antibodies to detect SLC3A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC3A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC3A1 antibodies...
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SLC3A1 Infographic by Boster Bio
All SLC3A1 Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A02654-2
100 μg/vial
Cat # A02654-2
100 μg/vial
SLC3A1 Overview
Facts about Neutral and basic amino acid transport protein rBAT.
Neutral and basic amino acid transport protein rBAT (SLC3A1)
Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like action ). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney tubule.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | SLC3A1 |
| Uniprot: | Q07837 |
| Entrez: | 6519 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
activator of cystine, dibasic and neutral amino acid transport), member 1; amino acid transporter 1; ATR1SLC3A1 variant C; B(0+)-type amino acid transport protein; CSNU1; D2h; D2HSLC3A1 variant D; dibasic and neutral amino acid transporters); FLJ34681; member 1; NBATneutral and basic amino acid transport protein rBAT; RBATSLC3A1 variant B; SLC3A1 variant E; SLC3A1 variant F; SLC3A1 variant G; solute carrier family 3 (cystine, dibasic and neutral amino acid transporters
Molecular Weight
Mass (kDA):
78.852 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p21 |
| Sequence: | 2; NC_000002.12 (44275464..44321494) |
Tissue Specificity
Expressed in the brush border membrane in the kidney (at protein level). Predominantly expressed in the kidney, small intestine and pancreas. Weakly expressed in liver.
Subcellular Localizations
Membrane; Single-pass type II membrane protein.
Diseases
- Cystinuria
- Kidney Calculi
- Nephrolithiasis
- Urolithiasis
- Aminoaciduria
- Hereditary Diseases
- Muscle Hypotonia
- Amino Acid Transport Disorder
- Lithiasis
- Kidney Failure
- Metabolic Diseases
- Dysequilibrium Syndrome
Pathways
- Transport
- Excretion
- Amino Acid Transport
- Localization
- Pathogenesis
- Neutral Amino Acid Transport
- Transepithelial Transport
- Reverse Transcription
- Phenylalanine Transport
- Transmembrane Transport
- L-cystine Transport
- Brain Development
- Proteolysis
PTMs
- Carboxylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC3A1
bosterbio.com/bosterbio-gene-info-cards/SLC3A1
References
PMID: 8486766 by Lee W.-S., et al. Cloning and chromosomal localization of a human kidney cDNA involved in cystine, dibasic, and neutral amino acid transport.
PMID: 7686906 by Bertran J., et al. Expression cloning of a human renal cDNA that induces high affinity transport of L-cystine shared with dibasic amino acids in Xenopus oocytes.