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- Table of Contents
Facts about Solute carrier family 49 member 4.
| Human | |
|---|---|
| Gene Name: | SLC49A4 |
| Uniprot: | Q96SL1 |
| Entrez: | 84925 |

| Belongs to: |
|---|
| major facilitator superfamily |

Solute carrier family 49 member 4
Mass (kDA):
52.088 kDA

| Human | |
|---|---|
| Location: | 3q21.1 |
| Sequence: | 3; NC_000003.12 (122795058..122892157) |
Ubiquitous. Expressed in proximal tubular cells of the kidney.
Lysosome membrane; Multi-pass membrane protein.


PMID: 11912179 by Bodmer D., et al. Disruption of a novel MFS transporter gene, DIRC2, by a familial renal cell carcinoma-associated t(2;3)(q35;q21).
PMID: 21692750 by Savalas L.R., et al. Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L.