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- Table of Contents
Facts about Sodium/myo-inositol cotransporter 2.
Also can transport D-chiro-inositol (DCI) but not L-fructose. Exhibits stereospecific cotransport of both D-glucose and D- xylose.
| Human | |
|---|---|
| Gene Name: | SLC5A11 |
| Uniprot: | Q8WWX8 |
| Entrez: | 115584 |

| Belongs to: |
|---|
| sodium:solute symporter (SSF) (TC 2.A.21) family |

Sodium/myo-inositol cotransporter 2
Mass (kDA):
74.036 kDA

| Human | |
|---|---|
| Location: | 16p12.1 |
| Sequence: | 16; NC_000016.10 (24845863..24911628) |
Highest expression in heart, skeletal muscle, kidney, liver and placenta. Weaker expression in brain, colon, spleen, lung and peripheral blood leukocytes.
Membrane; Multi-pass membrane protein.



PMID: 12039040 by Roll P., et al. New human sodium/glucose cotransporter gene (KST1): identification, characterization, and mutation analysis in ICCA (infantile convulsions and choreoathetosis) and BFIC (benign familial infantile convulsions) families.
PMID: 15172003 by Groenen P.M.W., et al. Spina bifida and genetic factors related to myo-inositol, glucose, and zinc.