SLC5A5 Antibodies

AND SLC5A5 ELISA kits, SLC5A5 Proteins

Many biological assays use antibodies to detect SLC5A5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC5A5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC5A5 antibodies...

We validate the specificity of these antibodies to SLC5A5 by testing them on tissues known to express SLC5A5 positively and negatively. Browse below to find the SLC5A5 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for SLC5A5? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SLC5A5 IHC Guide

SLC5A5 Infographic by Boster Bio

All SLC5A5 Products

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Product

Figures

Specificity

Applications

Price

Anti-SLC5A5 Antibody

IHC analysis of SLC5A5 using anti-SLC5A5 antibody (A04465-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IP, IHC, WB

$370
Cat # A04465-1
100 μl/vial

Sodium Iodide Symporter (SLC5A5) (NM_000453) Human Over-expression Lysate

Human

$628
Cat # LS006528
20 µg, 100 µg

Anti-Zebrafish SLC5A5 Antibody Picoband®

Western blot analysis of SLC5A5 using anti-SLC5A5 antibody (AZA4IG60)

Zebrafish

$470
Cat # AZA4IG60
100 μg/vial

SLC5A5 Overview

Facts about Sodium/iodide cotransporter.

SLC5A5 3D structure. Source: alphafold

Sodium/iodide cotransporter (SLC5A5)

Mediates iodide uptake in the thyroid gland. .

Gene Information

Human
Gene Name:	SLC5A5
Uniprot:	Q92911
Entrez:	6528

Family

Belongs to:

sodium:solute symporter (SSF) (TC 2.A.21) family

Alternative Names

Na(+)/I(-) cotransporter; Na(+)/I(-) symporter; NIS; NISNa(+)/I(-)-symporter; SLC5A5; sodium/iodide cotransporter; Sodium-iodide symporter; solute carrier family 5 (sodium iodide symporter), member 5; Solute carrier family 5 member 5; TDH1

Molecular Weight

Mass (kDA):
68.666 kDA

Genomic Context


Human

Location:	19p13.11
Sequence:	19; NC_000019.10 (17871394..17895175)

Tissue Specificity

Expression is primarily in thyroid tissue, but also to a lower extent in mammary gland and ovary. Expression is reduced in tumors.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Carcinoma
Malignant Neoplasms
Neoplasms
Cell Invasion
Malignant Neoplasm Of Prostate
Adenoma
Hypothyroidism
Tumor Progression
Curvature Of Spine
Thyroid Diseases
Carcinoma, Papillary
Neoplasm Invasiveness

Carcinogenesis
Thyroid Neoplasm
Metabolic Diseases
Prostatic Neoplasms
Obesity
Recurrent Prostate Carcinoma

Pathways

Transport
Iodide Transport
Cell Migration
Lactation
Fertilization
Ion Transport
Regulation Of Gene Expression
Energy Homeostasis
Dna Replication

Translation
Cell Motility
Locomotion
Hatching

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC5A5

References

PMID: 8806637 by Smanik P.A., et al. Cloning of the human sodium iodide symporter.

PMID: 9329364 by Saito T., et al. Increased expression of the Na+/I- symporter in cultured human thyroid cells exposed to thyrotropin and in Graves' thyroid tissue.