SLC5A7 Antibodies

AND SLC5A7 ELISA kits, SLC5A7 Proteins

Many biological assays use antibodies to detect SLC5A7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC5A7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC5A7 antibodies...

We validate the specificity of these antibodies to SLC5A7 by testing them on tissues known to express SLC5A7 positively and negatively. Browse below to find the SLC5A7 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC5A7 Infographic by Boster Bio

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Anti-SLC5A7 Antibody Picoband®

Western blot analysis of SLC5A7 using anti-SLC5A7 antibody (A05277-1)

Flow Cytometry analysis of JK cells using anti-SLC5A7 antibody (A05277-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A05277-1
100 μg/vial

SLC5A7 Overview

Facts about High affinity choline transporter 1.

SLC5A7 3D structure. Source: alphafold

High affinity choline transporter 1 (SLC5A7)

Transmembrane transporter that imports choline in the extracellular space into the neuron with high affinity. Choline uptake is the rate-limiting measure in acetylcholine synthesis.

Sodium ion- and chloride ion-dependent. .

Gene Information

Human
Gene Name:	SLC5A7
Uniprot:	Q9GZV3
Entrez:	60482

Family

Belongs to:

sodium:solute symporter (SSF) (TC 2.A.21) family

Alternative Names

CHT; CHT1MGC126299; hCHT; Hemicholinium-3-sensitive choline transporter; high affinity choline transporter 1; high affinity choline transporter; hemicholinium-3-sensitive cholinetransporter; MGC126300; solute carrier family 5 (choline transporter), member 7; Solute carrier family 5 member 7

Molecular Weight

Mass (kDA):
63.204 kDA

Genomic Context


Human

Location:	2q12.3
Sequence:	2; NC_000002.12 (107986524..108014497)

Tissue Specificity

Expressed in putamen, spinal cord and medulla. Specific for cholinergic neurons.

Subcellular Localizations

Membrane; Multi-pass membrane protein. Cell membrane. Cell junction, synapse. Localized at the neuromuscular junction.

Diseases

Malignant Neoplasms
Glioma
Neoplasms
Neuroblastoma
Alzheimer's Disease
Myasthenias
Carotid Artery Diseases
Malignant Neoplasm Of Breast
Neurodegenerative Disorders
Choline Deficiency
Ataxia
Colonic Neoplasms

Dementia
Swine Diseases
Malignant Tumor Of Colon
Carcinoma
Parkinson Disease
Nervousness
Asymptomatic Diseases

Pathways

Transport
Choline Transport
Cell Proliferation
Localization
Osteoblast Differentiation
Cellular Homeostasis
Endocytosis
Drug Resistance
System Development
Mast Cell Degranulation
Cell Death

Nervous System Development
Cell Differentiation
Keratinocyte Proliferation
Pathogenesis
Innervation
Secretion

PTMs

Ubiquitination

Research Areas

Neuroscience
Neurotransmission
Plasma Membrane Markers
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC5A7

References

PMID: 11027560 by Apparsundaram S., et al. Molecular cloning of a human, hemicholinium-3-sensitive choline transporter.

PMID: 11068039 by Okuda T., et al. Functional characterization of the human high-affinity choline transporter.