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- Table of Contents
SLC6A1 Antibodies
AND SLC6A1 ELISA kits, SLC6A1 Proteins
Many biological assays use antibodies to detect SLC6A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC6A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC6A1 antibodies...
Designing a Western blot for SLC6A1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SLC6A1 Western Blot GuideSLC6A1 Infographic by Boster Bio
All SLC6A1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, IHC, WB
$370
Cat # A05109
100 μg/vial
Cat # A05109
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A14901-2
100 μg/vial
Cat # A14901-2
100 μg/vial
SLC6A1 Overview
Facts about Sodium- and chloride-dependent GABA transporter 1.
Sodium- and chloride-dependent GABA transporter 1 (SLC6A1)
Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. .
Gene Information
| Human | |
|---|---|
| Gene Name: | SLC6A1 |
| Uniprot: | P30531 |
| Entrez: | 6529 |
Family
| Belongs to: |
|---|
| sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family |
Alternative Names
GABA Transporter 1; GABATHG; GABATR; GABATRGAT-1; GABT1; GAT1; GAT-1; GAT1sodium- and chloride-dependent GABA transporter 1; SLC6A1; solute carrier family 6 (neurotransmitter transporter, GABA), member 1; Solute carrier family 6 member 1
Molecular Weight
Mass (kDA):
67.074 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p25.3 |
| Sequence: | 3; NC_000003.12 (10992734..11039249) |
Subcellular Localizations
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Cell junction, synapse, presynapse. Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons (By similarity).
Diseases
- Epilepsy
- Schizophrenia
- Nervousness
- Pain
- Epilepsy, Temporal Lobe
- Hyperalgesia
- Depressive Disorder
- Neuralgia
- Malnutrition
- Ischemia
- Kindling, Neurologic
- Mental Disorders
Interacting Proteins
- DNAJC5
Pathways
- Transport
- Localization
- Synaptic Transmission
- Cellular Localization
- Pathogenesis
- Innervation
- Neurotransmitter Uptake
- Neurotransmitter Transport
- Ion Transport
- Associative Learning
- Reflex
- Cognition
- Exocytosis
PTMs
- Phosphorylation
- Biotinylation
- Cleavage
- Carboxylation
Research Areas
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC6A1
bosterbio.com/bosterbio-gene-info-cards/SLC6A1
References
PMID: 2387399 by Nelson H., et al. Cloning of the human brain GABA transporter.
PMID: 25865495 by Carvill G.L., et al. Mutations in the GABA Transporter SLC6A1 Cause Epilepsy with Myoclonic-Atonic Seizures.
5 Publications of Boster SLC6A1 Antibodies & ELISA Kits
- PubMed ID: PMID:32013288, Comparative Study of Chronic Postischemic Pain Models in Mice: O-Ring Versus Tie...
- PubMed ID: 10.3892/etm.2016.3148, Inhibition of the NMDA receptor protects the rat sciatic nerve against ischemia/...
- PubMed ID: 10.1167/iovs.17-22116, Glucocorticoid-Induced Leucine Zipper Protects the Retina From Light-Induced Ret...
- PubMed ID: 10.1111/1348-0421.12924, Protective Effect of Surfactin against Copper Sulfate-induced Inflammation, Oxid...
- PubMed ID: 10.1080/21691401.2019.1596936, Cell division cycle protein 42 regulates the inflammatory response in mice beari...
*More publications can be found for each product on its corresponding product page