- Table of Contents
Isoform 2 functions as low-affinity, higher capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine) (PubMed:9174363). May play a role in classical or other activation of macrophages through its role in arginine transport.
|amino acid-polyamine-organocation (APC) superfamily|
|Sequence:||8; NC_000008.11 (17494349..17570566)|
Expressed at high levels in the skeletal muscle, placenta and ovary. Expressed at intermediate levels in the liver and pancreas and at low levels in the kidney and heart.
Cell membrane; Multi-pass membrane protein.