SLIRP Antibodies

AND SLIRP ELISA kits, SLIRP Proteins

Many biological assays use antibodies to detect SLIRP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLIRP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLIRP antibodies...

We validate the specificity of these antibodies to SLIRP by testing them on tissues known to express SLIRP positively and negatively. Browse below to find the SLIRP antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for SLIRP? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SLIRP IHC Guide

SLIRP Infographic by Boster Bio

All SLIRP Products

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Product

Figures

Specificity

Applications

Price

Anti-SLIRP Antibody Picoband®

Western blot analysis of SLIRP using anti-SLIRP antibody (A08297-1)

IHC analysis of SLIRP using anti-SLIRP antibody (A08297-1)

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A08297-1
100 μg/vial

SLIRP (NM_031210) Human Over-expression Lysate

Human

$628
Cat # LS081892
20 µg, 100 µg

SLIRP (NM_031210) Human Recombinant Protein

Coomassie blue staining of purified SLIRP protein

$1249
Cat # PROTQ9GZT3
20 µg

SLIRP Overview

Facts about SRA stem-loop-interacting RNA-binding protein, mitochondrial.

SLIRP 3D structure. Source: alphafold

SRA stem-loop-interacting RNA-binding protein, mitochondrial (SLIRP)

RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation.

Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation.

Gene Information

Human
Gene Name:	SLIRP
Uniprot:	Q9GZT3
Entrez:	81892

Family

Belongs to:

No superfamily

Alternative Names

chromosome 14 open reading frame 156; DC50; PD04872; SLIRP; SRA stem-loop-interacting RNA-binding protein, mitochondrial

Molecular Weight

Mass (kDA):
12.349 kDA

Genomic Context


Human

Location:	14q24.3
Sequence:	14; NC_000014.9 (77708071..77717598)

Subcellular Localizations

Mitochondrion. Nucleus. Predominantly mitochondrial. Some fraction is nuclear. In the nucleus, it is recruited to nuclear receptor target promoters.

Diseases

Neoplasms
Neurodegenerative Disorders
Leigh Disease
Cardiomyopathies
Cytochrome-c Oxidase Deficiency
Azoospermia
Mammary Neoplasms

Peste Des Petits Ruminants Infection

Interacting Proteins

CCDC102B
KRT40
LRPPRC
MTUS2
PNMA1

WTAP

Pathways

Oxidative Phosphorylation
Translation
Mitochondrial Translation
Mrna Polyadenylation
Energy Homeostasis
Localization

Spermatogenesis

PTMs

Phosphorylation

Research Areas

Breast Cancer
Cancer
Chromatin Research
DNA replication, Transcription, Translation and Splicing
Signal Transduction

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLIRP

References

PMID: 16762838 by Hatchell E.C., et al. SLIRP, a small SRA binding protein, is a nuclear receptor corepressor.