SMPD3 Antibodies

AND SMPD3 ELISA kits, SMPD3 Proteins

Many biological assays use antibodies to detect SMPD3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SMPD3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SMPD3 antibodies...

We validate the specificity of these antibodies to SMPD3 by testing them on tissues known to express SMPD3 positively and negatively. Browse below to find the SMPD3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SMPD3 Infographic by Boster Bio

All SMPD3 Products

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Product

Figures

Specificity

Applications

Price

NSMase2 (SMPD3) (NM_018667) Human Over-expression Lysate

Human

$960
Cat # LS055512
20 µg, 100 µg

Anti-SMPD3 Antibody Picoband®

Western blot analysis of SMPD3 using anti-SMPD3 antibody (A04641)

Human

ELISA, WB

$370
Cat # A04641
100 µg/vial

SMPD3 Overview

Facts about Sphingomyelin phosphodiesterase 3.

SMPD3 3D structure. Source: alphafold

Sphingomyelin phosphodiesterase 3 (SMPD3)

Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 mobile events independently.

Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells.

Gene Information

Human
Gene Name:	SMPD3
Uniprot:	Q9NY59
Entrez:	55512

Family

Belongs to:

neutral sphingomyelinase family

Alternative Names

EC 3.1.4.12; FLJ22593; MGC138443; Neutral sphingomyelinase 2; Neutral sphingomyelinase II; NSMASE2; nSMase-2; SMPD3; sphingomyelin phosphodiesterase 3; sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinaseII)

Molecular Weight

Mass (kDA):
71.081 kDA

Genomic Context


Human

Location:	16q22.1
Sequence:	16; NC_000016.10 (68358327..68448703, complement)

Tissue Specificity

Predominantly expressed in brain.

Subcellular Localizations

Golgi apparatus membrane; Lipid-anchor. Cell membrane; Lipid-anchor. May localize to detergent-resistant subdomains of Golgi membranes of hypothalamic neurosecretory neurons (PubMed:10823942). Localizes to plasma membrane in confluent contact-inhaibited cells (PubMed:15051724).