SNRPD2 Antibodies

AND SNRPD2 ELISA kits, SNRPD2 Proteins

Many biological assays use antibodies to detect SNRPD2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SNRPD2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SNRPD2 antibodies...

We validate the specificity of these antibodies to SNRPD2 by testing them on tissues known to express SNRPD2 positively and negatively. Browse below to find the SNRPD2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for SNRPD2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SNRPD2 IHC Guide

SNRPD2 Infographic by Boster Bio

All SNRPD2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SNRPD2 Antibody Picoband®

Western blot analysis of SNRPD2 using anti-SNRPD2 antibody (A12026-1)

IHC analysis of SNRPD2 using anti-SNRPD2 antibody (A12026-1)

+13

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A12026-1
100 μg/vial

SNRPD2 (NM_004597) Human Over-expression Lysate

SNRPD2 Human Over-expression Lysates NM_004597

Human

$628
Cat # LS006633
20 µg, 100 µg

SNRPD2 (NM_004597) Human Recombinant Protein

Coomassie blue staining of purified SNRPD2 protein

$1249
Cat # PROTP62316
20 µg

SNRPD2 Overview

Facts about Small nuclear ribonucleoprotein Sm D2.

SNRPD2 3D structure. Source: alphafold

Small nuclear ribonucleoprotein Sm D2 (SNRPD2)

Plays role in pre-mRNA splicing as core part of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as part of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:23333303, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346).

Is also a part of the minor U12 spliceosome (PubMed:15146077). .

Gene Information

Human
Gene Name:	SNRPD2
Uniprot:	P62316
Entrez:	6633

Family

Belongs to:

snRNP core protein family

Alternative Names

small nuclear ribonucleoprotein D2 polypeptide (16.5kD); small nuclear ribonucleoprotein D2 polypeptide 16.5kDa; small nuclear ribonucleoprotein Sm D2; Sm-D2SMD2; snRNP core protein D2; SNRPD1

Molecular Weight

Mass (kDA):
13.527 kDA

Genomic Context


Human

Location:	19q13.32
Sequence:	19; NC_000019.10 (45687454..45692316, complement)

Subcellular Localizations

Cytoplasm, cytosol. Nucleus. SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.

Diseases

Autoimmune Reaction
Lupus Erythematosus, Systemic

Interacting Proteins

CEP70
CINP
CLNS1A
LSM2
LSM6

SNRPD1
SNRPF

Pathways

Immune Response

PTMs

Acetylation
Isopeptide bond

Phosphoprotein
Ubl conjugation

Research Areas

Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SNRPD2

References

PMID: 7527560 by Lehmeier T., et al. cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: evidence for a direct D1-D2 interaction.

PMID: 15146077 by Will C.L., et al. The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome.