Sorting nexin-17 Antibodies

AND SNX17 ELISA kits, Sorting nexin-17 Proteins

Many biological assays use antibodies to detect Sorting nexin-17, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sorting nexin-17 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sorting nexin-17 antibodies...

We validate the specificity of these antibodies to Sorting nexin-17 by testing them on tissues known to express SNX17 positively and negatively. Browse below to find the SNX17 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SNX17 Infographic by Boster Bio

All SNX17 Products

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Product

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Specificity

Applications

Price

SNX17 (NM_014748) Human Over-expression Lysate

Human

$628
Cat # LS009784
20 µg, 100 µg

Anti-SNX17 Antibody

Human, Mouse, Rat

ELISA, IP, IHC, WB

$370
Cat # A05515-1
100 μl/vial

SNX17 Overview

Facts about Sorting nexin-17.

SNX17 3D structure. Source: alphafold

Sorting nexin-17 (SNX17)

Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of goal cargos.

Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1.

Gene Information

Human
Gene Name:	SNX17
Uniprot:	Q15036
Entrez:	9784

Family

Belongs to:

sorting nexin family

Alternative Names

KIAA0064sorting nexin-17; sorting nexin 17

Molecular Weight

Mass (kDA):
52.901 kDA

Genomic Context


Human

Location:	2p23.3
Sequence:	2; NC_000002.12 (27370496..27377535)

Subcellular Localizations

Cytoplasm. Early endosome. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.

Diseases

Tissue Adhesions
Virus Diseases
Encephalopathy, Bovine Spongiform
Dna Virus Infections
Hypercholesterolemia, Familial
Atherosclerosis
Diabetes Mellitus
Hypercholesterolemia
Cavernous Hemangioma Of Brain

Hemangioma, Cavernous, Central Nervous System
Inflammation
Alzheimer's Disease
Bacterial Infections

Interacting Proteins

NCK1
PLCG1

Pathways

Endocytosis
Localization
Cell Adhesion
Transport
Cell Activation
Cell Migration
Endocytic Recycling
Dna Ligation
Cellular Localization
Wound Healing

Receptor Recycling
Pathogenesis
Exocytosis
Rna Interference
Monocyte Activation

PTMs

Phosphorylation

Cleavage

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SNX17

References

PMID: 11237770 by Florian V., et al. A new member of the sorting nexin family interacts with the C- terminus of P-selectin.

PMID: 14739284 by Burden J.J., et al. Sorting motifs in the intracellular domain of the low density lipoprotein receptor interact with a novel domain of sorting nexin- 17.