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- Table of Contents
Facts about Sorting nexin-33.
Required for normal formation of the cleavage furrow at the end of mitosis. Modulates endocytosis of cell-surface proteins, such as APP and PRNP; this then modulates the secretion of APP and PRNP peptides.
| Mouse | |
|---|---|
| Gene Name: | Snx33 |
| Uniprot: | Q4VAA7 |
| Entrez: | 235406 |

| Belongs to: |
|---|
| sorting nexin family |

MGC32065; SH3 and PX domain containing 3; SH3PXD3CSH3PX3; SNX30SH3 and PX domain-containing protein 3; sorting nexin 33; sorting nexin-33
Mass (kDA):
65.315 kDA

| Mouse | |
|---|---|
| Location: | 9|9 B |
| Sequence: | 9; |
Detected in brain (at protein level).




PMID: 18353773 by Schobel S., et al. A novel sorting nexin modulates endocytic trafficking and alpha- secretase cleavage of the amyloid precursor protein.
PMID: 26567222 by Ukken F.P., et al. BAR-SH3 sorting nexins are conserved interacting proteins of Nervous wreck that organize synapses and promote neurotransmission.