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Sorting nexin-4 Antibodies
AND SNX4 ELISA kits, Sorting nexin-4 Proteins
Many biological assays use antibodies to detect Sorting nexin-4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sorting nexin-4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sorting nexin-4 antibodies...
Designing an IHC experiment for Sorting nexin-4? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SNX4 IHC GuideSNX4 Infographic by Boster Bio
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SNX4 Overview
Facts about Sorting nexin-4.
Sorting nexin-4 (SNX4)
Involved in the regulation of endocytosis and in several stages of intracellular trafficking (PubMed:12668730). Plays a role in preventing endocytosed transferrin receptor and prevent its degradation.
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Gene Information
| Human | |
|---|---|
| Gene Name: | SNX4 |
| Uniprot: | O95219 |
| Entrez: | 8723 |
Family
| Belongs to: |
|---|
| sorting nexin family |
Alternative Names
ATG24B; sorting nexin 4; sorting nexin-4
Molecular Weight
Mass (kDA):
51.909 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3q21.2 |
| Sequence: | 3; NC_000003.12 (125446644..125520202, complement) |
Subcellular Localizations
Early endosome. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Also detected on a juxtanuclear endocytic recycling compartment (ERC).
Diseases
- Neoplasm Metastasis
- Malignant Neoplasms
- Juvenile Neuronal Ceroid Lipfuscinosis
- Neoplasms
- Malignant Neoplasm Of Breast
- Persistent Superficial Gastritis
- Mammary Neoplasms
Interacting Proteins
- ARL6IP1
- BIN1
- MAGEA6
- SNX30
- SNX7
Pathways
- Transport
- Localization
- Lipid Phosphorylation
- Ferrichrome Transport
- Dna Replication
- Membrane Tubulation
- Endocytic Recycling
- Endocytosis
- Receptor Recycling
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SNX4
bosterbio.com/bosterbio-gene-info-cards/SNX4
References
PMID: 9819414 by Haft C.R., et al. Identification of a family of sorting nexin molecules and characterization of their association with receptors.
PMID: 12668730 by Leprince C., et al. Sorting nexin 4 and amphiphysin 2, a new partnership between endocytosis and intracellular trafficking.