SORCS2 Antibodies

AND SORCS2 ELISA kits, SORCS2 Proteins

Many biological assays use antibodies to detect SORCS2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SORCS2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SORCS2 antibodies...

We validate the specificity of these antibodies to SORCS2 by testing them on tissues known to express SORCS2 positively and negatively. Browse below to find the SORCS2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: ALPK3

SORCS2 Infographic by Boster Bio

All SORCS2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SORCS2 Antibody

Human, Mouse, Rat

ELISA, WB

$370
Cat # A10767-1
100 μl/vial

SORCS2 Overview

Facts about VPS10 domain-containing receptor SorCS2.

SORCS2 3D structure. Source: alphafold

VPS10 domain-containing receptor SorCS2 (SORCS2)

Gene Information

Human
Gene Name:	SORCS2
Uniprot:	Q96PQ0
Entrez:	57537

Family

Belongs to:

VPS10-related sortilin family

Alternative Names

KIAA1329VPS10 domain receptor protein; SorCS2; sortilin-related VPS10 domain containing receptor 2; VPS10 domain-containing receptor SorCS2

Molecular Weight

Mass (kDA):
128.152 kDA

Genomic Context


Human

Location:	4p16.1
Sequence:	4; NC_000004.12 (7192538..7742828)

Tissue Specificity

Highly expressed in brain and kidney. Detected at low levels in heart, liver, small intestine, skeletal muscle and thymus.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Cell projection. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Early endosome membrane. Recycling endosome membrane. Cell junction, synapse, synaptosome. Perikaryon. Cell projection, dendrite. Cell projection, dendritic spine. Cell junction, synapse, postsynaptic density membrane.

Diseases

Nervousness
Alzheimer's Disease
Bipolar Disorder
Malignant Neoplasms
Neuroblastoma
Frontotemporal Lobar Degeneration
Cell Transformation, Neoplastic
Nerve Degeneration
Neurodegenerative Disorders
Nervous System Disorder
Schizophrenia
Tissue Adhesions

Atherosclerosis
Diabetes Mellitus
Parkinson Disease
Dysplasia
Diabetes Mellitus, Non-insulin-dependent
Cardiovascular Diseases

Pathways

Transport
Neurogenesis
Regulation Of Gene Expression
Endocytosis
Keratinocyte Differentiation
Protein Transport
System Development
Nervous System Development
Carbohydrate Homeostasis

Cell Growth
Regulation Of Cell Growth
Central Nervous System Development
Pathogenesis

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SORCS2

References

PMID: 11499680 by Hampe W., et al. The genes for the human VPS10 domain-containing receptors are large and contain many small exons.

PMID: 22155786 by Deinhardt K., et al. Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac.