SOS2 Antibodies

AND SOS2 ELISA kits, SOS2 Proteins

Many biological assays use antibodies to detect SOS2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SOS2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SOS2 antibodies...

We validate the specificity of these antibodies to SOS2 by testing them on tissues known to express SOS2 positively and negatively. Browse below to find the SOS2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for SOS2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the SOS2 Western Blot Guide

SOS2 Infographic by Boster Bio

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Anti-Son of sevenless homolog 2 SOS2 Antibody

Western blot (WB) analysis of SOS2 polyclonal antibody at 1:500 dilution
Lane1:Hela cell lysate
Lane2:sp2/0 cell lysate
Lane3:H9C2 cell lysate

Human, Mouse, Rat

ICC, WB

$405
Cat # A05957-1
100ul

SOS2 Overview

Facts about Son of sevenless homolog 2.

SOS2 3D structure. Source: alphafold

Son of sevenless homolog 2 (SOS2)

Promotes the exchange of Ras-bound GDP by GTP. .

Gene Information

Human
Gene Name:	SOS2
Uniprot:	Q07890
Entrez:	6655

Family

Belongs to:

No superfamily

Alternative Names

FLJ25596; guanine nucleotide exchange factor; guanine nucleotide releasing factor; son of sevenless (Drosophilia) homolog 2; son of sevenless homolog 2 (Drosophila); son of sevenless homolog 2; SOS2; SOS-2

Molecular Weight

Mass (kDA):
152.979 kDA

Genomic Context


Human

Location:	14q21.3
Sequence:	14; NC_000014.9 (50117130..50231578, complement)

Diseases

Physiological Stress
Dehydration
Neoplasms
Malignant Neoplasms
Cerebrovascular Accident
Tissue Adhesions
Metaplastic Cell Transformation
Neoplasm Metastasis
Mood Disorders
Anophthalmos
Carcinoma
Acute Cerebrovascular Accidents

Acute Erythroblastic Leukemia
Edema
Fibromatosis, Gingival
Chimera Disorder
Brain Injuries
Fibromatosis

Interacting Proteins

ABL1
CRK
GRB2
NCK1
PACSIN3

PLCG1
SNX9

Pathways

Ion Homeostasis
Transport
Localization
Cell Growth
Cell Migration
Cell Development
Response To Salt Stress
Germination
Cellular Ion Homeostasis
Translation
Seed Germination
Ion Transport
Cell Adhesion

Protein Phosphorylation
Cell Activation
Hyperphosphorylation
T Cell Activation
Cortical Microtubule Organization
Hypersensitivity
Regulation Of Ion Homeostasis

PTMs

Phosphorylation
Myristoylation

Biotinylation
Ribosylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SOS2

References

PMID: 8493579 by Chardin P., et al. Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.

PMID: 25795793 by Yamamoto G.L., et al. Rare variants in SOS2 and LZTR1 are associated with Noonan syndrome.