Spata13 Antibodies

AND Spata13 ELISA kits, Spata13 Proteins

Many biological assays use antibodies to detect Spata13, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Spata13 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Spata13 antibodies...

We validate the specificity of these antibodies to Spata13 by testing them on tissues known to express Spata13 positively and negatively. Browse below to find the Spata13 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Spata13 Infographic by Boster Bio

All Spata13 Products

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Price

SPATA13 (NM_153023) Human Over-expression Lysate

Human

$960
Cat # LS221178
20 µg, 100 µg

Anti-SPATA13 Antibody Picoband®

Western blot analysis of SPATA13 using anti-SPATA13 antibody (A09031-1)

Flow Cytometry analysis of RT4 cells using anti-SPATA13 antibody (A09031-1)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A09031-1
100 μg/vial

Spata13 Overview

Facts about Spermatogenesis-associated protein 13.

Spermatogenesis-associated protein 13 (Spata13)

Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly via a RAC1, PI3K, RHOA and AKT1-dependent mechanism.

Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA (By similarity). Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells.

Gene Information

Mouse
Gene Name:	Spata13
Uniprot:	Q5DU57
Entrez:	219140

Family

Belongs to:

No superfamily

Alternative Names

adenomatous polyposis coli stimulated exchange factor 2; FLJ35435; spermatogenesis associated 13

Molecular Weight

Mass (kDA):
75.257 kDA

Genomic Context


Mouse

Location:	14 D1\|14 31.77 cM
Sequence:	14;

Tissue Specificity

Expression is aberrantly enhanced in most colorectal tumors.

Diseases

Tissue Adhesions
Adenomatous Polyposis Coli
Neoplasms
Colorectal Neoplasms
Polyposis

Pathways

Cell Migration
Cell Adhesion
Rna Interference

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Spata13

References

PMID: 19893577 by Kawasaki Y., et al. The adenomatous polyposis coli-associated exchange factors Asef and Asef2 are required for adenoma formation in Apc(Min/+)mice.