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- Table of Contents
1 Citations 7 Q&As
Facts about Kunitz-type protease inhibitor 2.
Inhibitor of HGF activator.
Also inhibits plasmin, tissue and plasma kallikrein, and factor XIa..
| Human | |
|---|---|
| Gene Name: | SPINT2 |
| Uniprot: | O43291 |
| Entrez: | 10653 |

| Belongs to: |
|---|
| No superfamily |

HAI2; HAI-2; HAI-2DIAR3; HAI2FLJ45571; Hepatocyte growth factor activator inhibitor type 2; Kop; kunitz-type protease inhibitor 2; PB; Placental bikunin; serine peptidase inhibitor, Kunitz type, 2; serine protease inhibitor, Kunitz type, 2
Mass (kDA):
28.228 kDA

| Human | |
|---|---|
| Location: | 19q13.2 |
| Sequence: | 19; NC_000019.10 (38264573..38292615) |
Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea.
Membrane; Single-pass type I membrane protein.




PMID: 9346890 by Kawaguchi T., et al. Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor.
PMID: 9115294 by Marlor C.W., et al. Identification and cloning of human placental bikunin, a novel serine protease inhibitor containing two Kunitz domains.
*More publications can be found for each product on its corresponding product page