SPNS2 Antibodies

AND SPNS2 ELISA kits, SPNS2 Proteins

Many biological assays use antibodies to detect SPNS2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SPNS2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SPNS2 antibodies...

We validate the specificity of these antibodies to SPNS2 by testing them on tissues known to express SPNS2 positively and negatively. Browse below to find the SPNS2 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: MRPL10

SPNS2 Infographic by Boster Bio

All SPNS2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

SPNS2 Overview

Facts about Protein spinster homolog 2.

SPNS2 3D structure. Source: alphafold

Protein spinster homolog 2 (SPNS2)

Sphingolipid transporter required for migration of myocardial precursors. Transports sphingosine 1-phosphate (S1P), a secreted lipid mediator that plays critical roles in cardiovascular, immunological, and neural development and function.

Mediates the export of S1P from cells in the extraembryonic yolk syncytial layer (YSL), thereby regulating myocardial precursor migration. .

Gene Information

Human
Gene Name:	SPNS2
Uniprot:	Q8IVW8
Entrez:	124976

Family

Belongs to:

major facilitator superfamily

Alternative Names

protein spinster homolog 2; spinster homolog 2 (Drosophila)

Molecular Weight

Mass (kDA):
58.044 kDA

Genomic Context


Human

Location:	17p13.2
Sequence:	17; NC_000017.11 (4498881..4539035)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.

Diseases

Lymphopenia
Congenital Heart Defects
Autoimmune Reaction
Malignant Neoplasms
Craniofacial Abnormalities
Chimera Disorder
Crest Syndrome

Autoimmune Diseases

Pathways

Transport
Secretion
Heart Formation
Localization
Regulation Of Embryonic Development

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPNS2

References

PMID: 19074308 by Kawahara A., et al. The sphingolipid transporter spns2 functions in migration of zebrafish myocardial precursors.

PMID: 23180825 by Nagahashi M., et al. Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network.