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- Table of Contents
Facts about Protein sprouty homolog 3.
| Human | |
|---|---|
| Gene Name: | SPRY3 |
| Uniprot: | O43610 |
| Entrez: | 10251 |

| Belongs to: |
|---|
| sprouty family |

Antagonist Of FGF Signaling; HSPRY3; Protein Sprouty Homolog 3; sprouty (Drosophila) homolog 2; Sprouty Homolog 3 (Drosophila); SPRY3; spry-3
Mass (kDA):
31.222 kDA

| Human | |
|---|---|
| Location: | Xq28 and Yq12 |
| Sequence: | X|Y; NC_000023.11 (155612565..155782459) |
Widely expressed; particularly in the fetal tissues.
Cytoplasm. Membrane; Peripheral membrane protein. Found in the cytoplasm in unstimulated cells but is translocated to the membrane ruffles in cells stimulated with EGF (epidermal growth factor).




PMID: 10655549 by Ciccodicola A., et al. Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region.
PMID: 9458049 by Hacohen N., et al. Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways.