Sptssb Antibodies

AND Sptssb ELISA kits, Sptssb Proteins

Many biological assays use antibodies to detect Sptssb, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sptssb in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sptssb antibodies...

We validate the specificity of these antibodies to Sptssb by testing them on tissues known to express Sptssb positively and negatively. Browse below to find the Sptssb antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Sptssb Infographic by Boster Bio

All Sptssb Products

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SPTSSB (NM_001040100) Human Recombinant Protein

Coomassie blue staining of purified SPTSSB protein

$1062
Cat # PROTQ8NFR3
20 µg

SPTSSB (NM_001040100) Human Over-expression Lysate

Human

$628
Cat # LS165679
20 µg, 100 µg

Sptssb Overview

Facts about Serine palmitoyltransferase small subunit B.

Serine palmitoyltransferase small subunit B (Sptssb)

Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference, complexes with this subunit showing a clear preference for more acyl-CoAs.

The SPTLC1-SPTLC2-SPTSSB complex indicates a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme shows an ability to utilize a broader range of acyl-CoAs, without apparent preference (By similarity). .

Gene Information

Mouse
Gene Name:	Sptssb
Uniprot:	Q925E8
Entrez:	66183

Family

Belongs to:

SPTSS family

Alternative Names

Serine palmitoyltransferase small subunit B

Molecular Weight

Mass (kDA):
9.108 kDA

Genomic Context


Mouse

Location:	3\|3 E2
Sequence:	3;

Tissue Specificity

Expression is strong in hypogonadal (hpg) mouse prostate, weak in mature castrated mouse prostate and absent in normal intact or androgen-replaced hpg mouse prostates.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Sptssb

References

PMID: 15777716 by Singh J., et al. Molecular cloning and characterization of a novel androgen repressible gene expressed in the prostate epithelium.

PMID: 26438849 by Zhao L., et al. Elevation of 20-carbon long chain bases due to a mutation in serine palmitoyltransferase small subunit b results in neurodegeneration.