Spexin Antibodies

AND SPX ELISA kits, Spexin Proteins

Many biological assays use antibodies to detect Spexin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Spexin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Spexin antibodies...

We validate the specificity of these antibodies to Spexin by testing them on tissues known to express SPX positively and negatively. Browse below to find the SPX antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SPX Infographic by Boster Bio

All SPX Products

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Product

Figures

Specificity

Applications

Price

Anti-SPXN Antibody

Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night

Human, Mouse, Rat

ELISA, WB

$380
Cat # A04088-2
100ul

SPX (NM_030572) Human Over-expression Lysate

Human

$628
Cat # LS080763
20 µg, 100 µg

SPX Overview

Facts about Spexin.

SPX 3D structure. Source: alphafold

Spexin (SPX)

Plays a role as a central modulator of cardiovascular and renal function and nociception. Plays also a role in energy metabolism and storage.

Inhibits adrenocortical cell proliferation with minor stimulation on corticosteroid release (By similarity). .

Gene Information

Human
Gene Name:	SPX
Uniprot:	Q9BT56
Entrez:	80763

Family

Belongs to:

spexin family

Alternative Names

Spexin

Molecular Weight

Mass (kDA):
13.302 kDA

Genomic Context


Human

Location:	12p12.1
Sequence:	12; NC_000012.12 (21526296..21532947)

Tissue Specificity

Expressed in the type I glomic cells within the carotid body (at protein level). Expressed predominantly in pancreas, testis, kidney, brain and placenta. Expressed in submucosal layer of esophagus and stomach fundus.

Subcellular Localizations

Secreted. Secreted, extracellular space. Cytoplasmic vesicle, secretory vesicle. Secreted via the classical ER/Golgi-dependent pathway into the extracellular medium largely as a full-length protein without the signal peptide, and not as a hydrolyzed and amidated peptide (PubMed:19193193 and PubMed:17284679). Localized extracellularly surrounding the villous trophoblastic cells. Detected in the serum.

PTMs

Amidation

Cleavage on pair of basic residues

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPX

References

PMID: 19132080 by Sonmez K., et al. Evolutionary sequence modeling for discovery of peptide hormones.

PMID: 17284679 by Mirabeau O., et al. Identification of novel peptide hormones in the human proteome by hidden Markov model screening.