Srcin1 Antibodies

AND Srcin1 ELISA kits, Srcin1 Proteins

Many biological assays use antibodies to detect Srcin1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Srcin1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Srcin1 antibodies...

We validate the specificity of these antibodies to Srcin1 by testing them on tissues known to express Srcin1 positively and negatively. Browse below to find the Srcin1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: Hebp2

Srcin1 Infographic by Boster Bio

All Srcin1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-p140Cap SRCIN1 Antibody

4 Q&As

Human, Mouse, Rat

ELISA, WB

$399
Cat # A08110
100μl

Anti-SRCIN1 Antibody Picoband®

1 Q&As

Western blot analysis of SRCIN1 using anti-SRCIN1 antibody (A08110-1)

IHC analysis of SRCIN1 using anti-SRCIN1 antibody (A08110-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, IHC-F, ICC, WB

$370
Cat # A08110-1
100 μg/vial

Srcin1 Overview

Facts about SRC kinase signaling inhibitor 1.

SRC kinase signaling inhibitor 1 (Srcin1)

Acts as a negative regulator of SRC by sparking CSK which inhibits SRC activity and downstream signaling, resulting in impaired cell spreading and migration. Regulates dendritic spine morphology.

Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance (By similarity).

Gene Information

Mouse
Gene Name:	Srcin1
Uniprot:	Q9QWI6
Entrez:	56013

Family

Belongs to:

SRCIN1 family

Alternative Names

KIAA1684P140; p130Cas-associated protein; p140CapSNAP25-interacting protein; SNIPSNAP-25-interacting protein; SRC kinase signaling inhibitor 1

Molecular Weight

Mass (kDA):
134.859 kDA

Genomic Context


Mouse

Location:	11\|11 D
Sequence:	11;

Tissue Specificity

Expressed predominantly in central nervous system with high levels detected in cortex, cerebellum, midbrain and spinal cord (at protein level). Also expressed in testis and epithelial-rich tissues such as mammary gland, lung and kidney.

Diseases

Malignant Neoplasms
Neoplasms
Tumor Progression
Metaplastic Cell Transformation
Tissue Adhesions
Neoplasm Invasiveness

PTMs

Methylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Srcin1

References

PMID: 14657239 by Di Stefano P., et al. p130Cas-associated protein (p140Cap) as a new tyrosine-phosphorylated protein involved in cell spreading.

PMID: 19146815 by Jaworski J., et al. Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity.