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Srek1 Antibodies
AND Srek1 ELISA kits, Srek1 Proteins
Many biological assays use antibodies to detect Srek1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Srek1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Srek1 antibodies...
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Srek1 Overview
Facts about Splicing regulatory glutamine/lysine-rich protein 1.
Splicing regulatory glutamine/lysine-rich protein 1 (Srek1)
Participates in the regulation of alternative splicing by modulating the activity of additional splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6.
Augments the splicing activity of SFRS3. .
Gene Information
| Rat | |
|---|---|
| Gene Name: | Srek1 |
| Uniprot: | Q9JKL7 |
| Entrez: | 56763 |
Family
| Belongs to: |
|---|
| splicing factor SR family |
Alternative Names
DKFZp564B176; Serine/arginine-rich-splicing regulatory protein 86; SFRS12serine-arginine-rich-splicing regulatory protein 86; Splicing factor, arginine/serine-rich 12MGC133045; splicing regulatory glutamine/lysine-rich protein 1; Splicing regulatory protein 508; SRRp508; SRrp508SRrp86serine-arginine-rich splicing regulatory protein 508; SRRP86
Molecular Weight
Mass (kDA):
56.849 kDA
Genomic Context
| Rat | |
|---|---|
| Location: | 2q12 |
| Sequence: | 2; |
Tissue Specificity
Ubiquitous. Detected in liver, brain, lung, spleen, testis and pancreas.
Diseases
- Neurodegenerative Disorders
- Dementia
- Alzheimer's Disease
Pathways
- Reverse Transcription
- Aging
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Srek1
bosterbio.com/bosterbio-gene-info-cards/Srek1
References
PMID: 10757789 by Barnard D.C., et al. Identification and characterization of a novel serine-arginine-rich splicing regulatory protein.
PMID: 11991645 by Barnard D.C., et al. Regulation of alternative splicing by SRrp86 through coactivation and repression of specific SR proteins.