SRGAP2C Antibodies

AND SRGAP2C ELISA kits, SRGAP2C Proteins

Many biological assays use antibodies to detect SRGAP2C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SRGAP2C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SRGAP2C antibodies...

We validate the specificity of these antibodies to SRGAP2C by testing them on tissues known to express SRGAP2C positively and negatively. Browse below to find the SRGAP2C antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SRGAP2C Infographic by Boster Bio

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SRGAP2C Overview

Facts about SLIT-ROBO Rho GTPase-activating protein 2C.

SRGAP2C 3D structure. Source: alphafold

SLIT-ROBO Rho GTPase-activating protein 2C (SRGAP2C)

Involved in dendritic spine maturation through interaction with and inhibition of SRGAP2. Reduces the rate of spine maturation and indirectly increases neuronal migration.

Changes dendritic spine morphology and density and might have consequences for cognition, memory and learning. .

Gene Information

Human
Gene Name:	SRGAP2C
Uniprot:	P0DJJ0
Entrez:	653464

Family

Belongs to:

No superfamily

Alternative Names

SLIT-ROBO Rho GTPase-activating protein 2C

Molecular Weight

Mass (kDA):
53.484 kDA

Genomic Context


Human

Location:	1p11.2
Sequence:	1; NC_000001.11 (121184975..121392874)

Tissue Specificity

Ubiquitously expressed with higher expression in cerebellum. Probably expressed in fetal and adult neurons (at protein level).

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SRGAP2C

References

PMID: 22559944 by Charrier C., et al. Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation.

PMID: 22559943 by Dennis M.Y., et al. Evolution of human-specific neural SRGAP2 genes by incomplete segmental duplication.