SRRM2 Antibodies

AND SRRM2 ELISA kits, SRRM2 Proteins

Many biological assays use antibodies to detect SRRM2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SRRM2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SRRM2 antibodies...

We validate the specificity of these antibodies to SRRM2 by testing them on tissues known to express SRRM2 positively and negatively. Browse below to find the SRRM2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for SRRM2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SRRM2 IHC Guide

SRRM2 Infographic by Boster Bio

All SRRM2 Products

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Applications

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Anti-SRRM2 Antibody

Immunohistochemical analysis of paraffin-embedded human Small intestinal stromal tumor

Human, Mouse

IF, IHC

$380
Cat # A07592
100ul

SRRM2 Overview

Facts about Serine/arginine repetitive matrix protein 2.

Serine/arginine repetitive matrix protein 2 (SRRM2)

Involved in pre-mRNA splicing. May function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome.

May do this by stabilizing the catalytic center or the place of the RNA substrate (By similarity). Binds to RNA.

Gene Information

Human
Gene Name:	SRRM2
Uniprot:	Q9UQ35
Entrez:	23524

Family

Belongs to:

CWC21 family

Alternative Names

Cwc21; CWF21; DKFZp667L0421,300 kDa nuclear matrix antigen; DKFZp686O15166,300-KD; FLJ21926; FLJ22250; HSPC075; KIAA0324; MGC40295; RNA binding protein; ser/Arg-related nuclear matrix protein of 300 kDa; serine/arginine repetitive matrix 2; serine/arginine repetitive matrix protein 2; serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa; splicing coactivator subunit SRm300; SRL300; SRM300; SR-related nuclear matrix protein of 300 kDa; taxREB803; tax-responsive enhancer element-binding protein 803

Molecular Weight

Mass (kDA):
299.615 kDA

Genomic Context


Human

Location:	16p13.3
Sequence:	16; NC_000016.10 (2750903..2771412)

Tissue Specificity

Expressed in liver, placenta, and white blood cells.

Subcellular Localizations

Nucleus. Nucleus speckle.

Diseases

Tissue Adhesions
Neoplasm Metastasis
Malignant Neoplasms
Neurodegenerative Disorders
Malignant Neoplasm Of Ovary
Parkinson Disease

Pathways

Epithelial Cell-cell Adhesion
Rna Splicing
Cell-cell Adhesion
Protein Phosphorylation
Cell Adhesion
Cell Proliferation
Cell Cycle

Rna Processing

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SRRM2

References

PMID: 11004489 by Sawada Y., et al. Cloning and characterization of a novel RNA-binding protein SRL300 with RS domains.

PMID: 10668804 by Blencowe B.J., et al. The SRm160/300 splicing coactivator subunits.