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- Table of Contents
Facts about Serine/arginine-rich splicing factor 10.
Required for splicing repression in M-phase cells and after heat shock (PubMed:14765198). Also functions as a splicing factor that specifically promotes exon skipping during alternative splicing (PubMed:26876937).
| Human | |
|---|---|
| Gene Name: | SRSF10 |
| Uniprot: | O75494 |
| Entrez: | 10772 |

| Belongs to: |
|---|
| splicing factor SR family |

40 kDa SR-repressor protein; FLJ43846; FUS interacting protein (serine-arginine rich) 1; FUS-interacting protein (serine-arginine rich) 2; FUS-interacting serine-arginine-rich protein 1; FUSIP1DKFZp686H0644; FUSIP2; neural-salient SR protein; NSSR; serine/arginine-rich splicing factor 10; serine-arginine repressor protein (40 kDa); SFRS13; SFRS13A; Splicing factor SRp38; splicing factor, arginine/serine-rich 13; Splicing factor, arginine/serine-rich 13ATLS-associated protein with Ser-Arg repeats; SR splicing factor 10; SRp38; SRrp40TLS-associated protein with SR repeats; TASR1TLS-associated SR
Mass (kDA):
31.301 kDA

| Human | |
|---|---|
| Location: | 1p36.11 |
| Sequence: | 1; NC_000001.11 (23964347..23980370, complement) |
Widely expressed.
Nucleus speckle. Cytoplasm.





PMID: 9774382 by Yang L., et al. Oncoprotein TLS interacts with serine-arginine proteins involved in RNA splicing.
PMID: 10779324 by Yang L., et al. TLS-ERG leukemia fusion protein inhibits RNA splicing mediated by serine-arginine proteins.