Serine/arginine-rich splicing factor 10 (SRSF10)

Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing (PubMed:11684676, PubMed:12419250, PubMed:14765198). Appears to interfere with the U1 snRNP 5'-splice recognition of SNRNP70 (PubMed:14765198).

Required for splicing repression in M-phase cells and after heat shock (PubMed:14765198). Also functions as a splicing factor that specifically promotes exon skipping during alternative splicing (PubMed:26876937).