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- Table of Contents
ST3GAL3 Antibodies
AND ST3GAL3 ELISA kits, ST3GAL3 Proteins
Many biological assays use antibodies to detect ST3GAL3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ST3GAL3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ST3GAL3 antibodies...
Designing an IHC experiment for ST3GAL3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the ST3GAL3 IHC GuideST3GAL3 Infographic by Boster Bio
All ST3GAL3 Products
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Specificity
Applications
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ST3GAL3 Overview
Facts about CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase.
CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase (ST3GAL3)
Catalyzes the formation of this NeuAc-alpha-2,3-Gal-beta- 1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alpha- 2,3-Gal-beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta-1,3-GlcNAc and the lowest toward Gal-beta-1,3- GalNAc.
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Gene Information
| Human | |
|---|---|
| Gene Name: | ST3GAL3 |
| Uniprot: | Q11203 |
| Entrez: | 6487 |
Family
| Belongs to: |
|---|
| glycosyltransferase 29 family |
Alternative Names
alpha 2,3-sialyltransferase III; Alpha 2,3-ST 3; alpha-2,3-sialyltransferase II; Beta-galactoside alpha-2,3-sialyltransferase 3; CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase; EC 2.4.99.6; Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase; Gal beta-1,3(4)GlcNAc alpha-2,3 sialyltransferase; MRT12; N-acetyllactosaminide alpha-2,3-sialyltransferase; Sialyltransferase 6; Siat3; SIAT6; SIAT6sialyltransferase 6 (N-acetyllacosaminide alpha 2,3-sialyltransferase); ST3 beta-Gal alpha-2,3-Sialyltransferase 3; ST3 beta-galactoside alpha-2,3-sialyltransferase 3; ST3Gal III; ST3
Molecular Weight
Mass (kDA):
42.171 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p34.1 |
| Sequence: | 1; NC_000001.11 (43707465..43931165) |
Tissue Specificity
Highly expressed in adult skeletal muscle and in all fetal tissues examined and to a much lesser extent in placenta, lung and liver.
Subcellular Localizations
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
Diseases
- Inflammation
- Cell Invasion
- Stomach Neoplasms
- Malignant Neoplasm Of Prostate
- Neoplasm Metastasis
- Tumor Progression
- Tissue Adhesions
- Autonomic Dysreflexia
- Gastrointestinal Carcinoma
- Neoplasm Invasiveness
- Carcinoma
Pathways
- Regeneration
- Tissue Regeneration
- Cell Motility
- Cell Differentiation
- Glycosylation
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ST3GAL3
bosterbio.com/bosterbio-gene-info-cards/ST3GAL3
References
PMID: 8333853 by Kitagawa H., et al. Cloning and expression of human Gal beta 1,3(4)GlcNAc alpha 2,3- sialyltransferase.
PMID: 21907012 by Hu H., et al. ST3GAL3 mutations impair the development of higher cognitive functions.