STARD8 Antibodies

AND STARD8 ELISA kits, STARD8 Proteins

Many biological assays use antibodies to detect STARD8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with STARD8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop STARD8 antibodies...

We validate the specificity of these antibodies to STARD8 by testing them on tissues known to express STARD8 positively and negatively. Browse below to find the STARD8 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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STARD8 Infographic by Boster Bio

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STARD8 (NM_014725) Human Over-expression Lysate

Human

$628
Cat # LS009754
20 µg, 100 µg

STARD8 Overview

Facts about StAR-related lipid transfer protein 8.

STARD8 3D structure. Source: alphafold

StAR-related lipid transfer protein 8 (STARD8)

Accelerates GTPase activity of RHOA and CDC42, but not RAC1.
Stimulates the hydrolysis of phosphatidylinositol 4,5- bisphosphate by PLCD1.

Gene Information

Human
Gene Name:	STARD8
Uniprot:	Q92502
Entrez:	9754

Family

Belongs to:

No superfamily

Alternative Names

ARHGAP38; Deleted in liver cancer 3 protein; DKFZp686H1668; DLC3DLC-3; KIAA0189stAR-related lipid transfer protein 8; StARD8; StAR-related lipid transfer (START) domain containing 8; START domain containing 8; START domain-containing protein 8; STARTGAP3; START-GAP3

Molecular Weight

Mass (kDA):
112.601 kDA

Genomic Context


Human

Location:	Xq13.1
Sequence:	X; NC_000023.11 (68647669..68725842)

Tissue Specificity

Widely expressed with highest levels in kidney, lung and placenta.

Subcellular Localizations

Cell junction, focal adhesion.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Breast
Carcinogenesis
Carcinoma
Malignant Neoplasm Of Kidney
Craniofacial Abnormalities
Malignant Neoplasm Of Liver
Orbital Separation Excessive
Sex Chromosome Disorders
Chondrosarcoma
Craniosynostosis

Mammary Neoplasms
Cytogenetic Abnormality
Colorectal Cancer
Congenital Diaphragmatic Hernia
Embryonic Mosaic
Malignant Neoplasm Of Prostate
Cell Transformation, Neoplastic

Pathways

Methylation
Diaphragm Development
Cell Proliferation
Cell Growth

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/STARD8

References

PMID: 17976533 by Kawai K., et al. START-GAP3/DLC3 is a GAP for RhoA and Cdc42 and is localized in focal adhesions regulating cell morphology.

PMID: 17297465 by Durkin M.E., et al. Deleted in liver cancer 3 (DLC-3), a novel Rho GTPase-activating protein, is downregulated in cancer and inhibits tumor cell growth.