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- Table of Contents
STAT5B Antibodies
AND STAT5B ELISA kits, STAT5B Proteins
Many biological assays use antibodies to detect STAT5B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with STAT5B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop STAT5B antibodies...
Designing a Western blot for STAT5B? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the STAT5B Western Blot GuideDesigning an IHC experiment for STAT5B? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the STAT5B IHC GuideSTAT5B Infographic by Boster Bio
All STAT5B Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, ICC, WB
$370
Cat # PB9512
100 μg/vial
Cat # PB9512
100 μg/vial
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M00681
100 μl
Cat # M00681
100 μl
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01087-3
20μL, 40μL, 100μL, 200μL
Cat # M01087-3
20μL, 40μL, 100μL, 200μL
STAT5B Overview
Facts about Signal transducer and activator of transcription 5B.
Signal transducer and activator of transcription 5B (STAT5B)
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors.
Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation.
Gene Information
| Human | |
|---|---|
| Gene Name: | STAT5B |
| Uniprot: | P51692 |
| Entrez: | 6777 |
Family
| Belongs to: |
|---|
| transcription factor STAT family |
Alternative Names
signal transducer and activator of transcription 5B; STAT5; STAT5b; transcription factor STAT5B
Molecular Weight
Mass (kDA):
89.866 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q21.2 |
| Sequence: | 17; NC_000017.11 (42199177..42288437, complement) |
Subcellular Localizations
Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.
Diseases
- Neoplasms
- Janiceps
- Malignant Neoplasms
- Leukemia
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Cell Transformation, Neoplastic
- Dwarfism
- Carcinoma
- Pituitary Diseases
- Growth Disorders
- Immunologic Deficiency Syndromes
Interacting Proteins
- DNAJA3
- NMI
Pathways
- Cell Proliferation
- Secretion
- Localization
- Cell Cycle
- Cell Growth
- Pathogenesis
- Cell Death
- Lactation
- Cell Differentiation
- Cell Development
- Gland Development
- Mammary Gland Development
- Cell Motility
PTMs
- Phosphorylation
- Dephosphorylation
- Methylation
- Cleavage
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/STAT5B
bosterbio.com/bosterbio-gene-info-cards/STAT5B
References
PMID: 8732682 by Silva C.M., et al. Characterization and cloning of STAT5 from IM-9 cells and its activation by growth hormone.
PMID: 8631883 by Lin J.-X., et al. Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells.
2 Publications of Boster STAT5B Antibodies & ELISA Kits
- PubMed ID: 10.1111/cen.14148, Severe growth failure associated with a novel heterozygous nonsense mutation in ...
- PubMed ID: 33975196, Ocaranza P,Íñiguez G,Johnson MC,Cassorla F.Differential effects of androgens a...
*More publications can be found for each product on its corresponding product page