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- Table of Contents
Designing an IHC experiment for Metalloreductase STEAP1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the STEAP1 IHC GuideFacts about Metalloreductase STEAP1.
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+).
Uses NAD(+) as acceptor (By similarity).. .
| Human | |
|---|---|
| Gene Name: | STEAP1 |
| Uniprot: | Q9UHE8 |
| Entrez: | 26872 |

| Belongs to: |
|---|
| STEAP family |

EC 1.16.1.-; PRSS24; PRSS24MGC19484; six transmembrane epithelial antigen of the prostate 1; six transmembrane epithelial antigen of the prostate; Six-transmembrane epithelial antigen of prostate 1; STEAP1; STEAPmetalloreductase STEAP1
Mass (kDA):
39.851 kDA

| Human | |
|---|---|
| Location: | 7q21.13 |
| Sequence: | 7; NC_000007.14 (90154469..90164827) |
Ubiquitously expressed. Highly expressed in prostate tumors.
Endosome membrane; Multi-pass membrane protein.





PMID: 10588738 by Hubert R.S., et al. STEAP: a prostate-specific cell-surface antigen highly expressed in human prostate tumors.
PMID: 16609065 by Ohgami R.S., et al. The Steap proteins are metalloreductases.