STK25 Antibodies

AND STK25 ELISA kits, STK25 Proteins

Many biological assays use antibodies to detect STK25, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with STK25 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop STK25 antibodies...

We validate the specificity of these antibodies to STK25 by testing them on tissues known to express STK25 positively and negatively. Browse below to find the STK25 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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STK25 Infographic by Boster Bio

All STK25 Products

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STK25 (NM_006374) Human Over-expression Lysate

Human

$628
Cat # LS010494
20 µg, 100 µg

Anti-STK25 Antibody Picoband®

Western blot analysis of STK25 using anti-STK25 antibody (A06816-1)

Flow Cytometry analysis of U251 cells using anti-STK25 antibody (A06816-1)

Human

ELISA, Flow Cytometry, WB

$370
Cat # A06816-1
100 μg/vial

STK25 Overview

Facts about Serine/threonine-protein kinase 25.

STK25 3D structure. Source: alphafold

Serine/threonine-protein kinase 25 (STK25)

Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets into the Golgi apparatus where it seems to regulate protein transport occasions, cell adhesion, and polarity complexes important for cell migration.

Gene Information

Human
Gene Name:	STK25
Uniprot:	O00506
Entrez:	10494

Family

Belongs to:

protein kinase superfamily

Alternative Names

EC 2.7.11; EC 2.7.11.1; serine/threonine kinase 25 (Ste20, yeast homolog); serine/threonine kinase 25; serine/threonine-protein kinase 25; SOK-1; SOK1DKFZp686J1430; Ste20, yeast homolog; Ste20/oxidant stress response kinase 1; sterile 20 (oxidant stress response kinase 1; yeast Sps1/Ste20-related kinase1); Sterile 20/oxidant stress-response kinase 1; YSK1yeast)

Molecular Weight

Mass (kDA):
48.112 kDA

Genomic Context


Human

Location:	2q37.3
Sequence:	2; NC_000002.12 (241492670..241509730, complement)

Tissue Specificity

Ubiquitously expressed. Highest levels are found in testis, large intestine, brain and stomach followed by heart and lung.

Subcellular Localizations

Cytoplasm. Golgi apparatus. Localizes to the Golgi apparatus.

Diseases

Cavernous Hemangioma Of Brain
Neoplasms
Cerebrovascular Accident
Neoplasm Metastasis
Pseudohypoparathyroidism
Malignant Neoplasms
Headache
Pseudopseudohypoparathyroidism
Brachydactyly
Cell Invasion
Hemangioma, Cavernous, Central Nervous System
Cardiovascular Abnormalities

Pediatric Neoplasm
Tumor Progression
Malignant Neoplasm Of Breast
Neurodegenerative Disorders
Myeloid Leukemia, Chronic
Carcinogenesis

Interacting Proteins

CAB39
CCDC36
CEP70
GOLGA2
Golga2

PDCD10
STRN
TRIM27
YWHAZ

Pathways

Cell Death
Hyperphosphorylation
Cell Migration
Cell Growth
Transport
Cell Adhesion
Golgi Localization
Cell Proliferation
Brain Development
Protein Transport
Localization
Ion Homeostasis

Lipid Oxidation
Golgi Organization
Angiogenesis
Pathogenesis
Rna Interference
Secretion

PTMs

Phosphorylation
Dephosphorylation

Reduction
Cleavage

Oxidation

Research Areas

Protein Kinase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/STK25

References

PMID: 8887545 by Pombo C.M., et al. Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway.

PMID: 9160885 by Osada S., et al. YSK1, a novel mammalian protein kinase structurally related to Ste20 and SPS1, but is not involved in the known MAPK pathways.