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- Table of Contents
STOML2 Antibodies
AND STOML2 ELISA kits, STOML2 Proteins
Many biological assays use antibodies to detect STOML2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with STOML2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop STOML2 antibodies...
Designing an IHC experiment for STOML2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the STOML2 IHC GuideSTOML2 Infographic by Boster Bio
All STOML2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IHC, WB
$370
Cat # A04108-1
100 μg/vial
Cat # A04108-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # M04108-1
100 μl/vial
Cat # M04108-1
100 μl/vial
STOML2 Overview
Facts about Stomatin-like protein 2, mitochondrial.
Stomatin-like protein 2, mitochondrial (STOML2)
Mitochondrial protein that likely regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins such as prohibitin and might therefore act in the organization of functional microdomains in mitochondrial membranes.
Through regulation of the adrenal function may play a role into several biological processes such as cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria.
Gene Information
| Human | |
|---|---|
| Gene Name: | STOML2 |
| Uniprot: | Q9UJZ1 |
| Entrez: | 30968 |
Family
| Belongs to: |
|---|
| band 7/mec-2 family |
Alternative Names
EPB72-like protein 2; HSPC108; SLP2; SLP-2stomatin-like protein 2; stomatin (EPB72)-like 2; stomatin-like 2
Molecular Weight
Mass (kDA):
38.534 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9p13.3 |
| Sequence: | 9; NC_000009.12 (35099776..35103195, complement) |
Tissue Specificity
Ubiquitously expressed at low levels. Expressed in lymphoid tissues (at protein level).
Subcellular Localizations
Cell membrane; Peripheral membrane protein. Mitochondrion. Mitochondrion inner membrane; Lipid-anchor. Mitochondrion intermembrane space. Membrane raft. Cytoplasm, cytoskeleton. Behaves as an integral membrane protein of the mitochondrion despite the absence of a detectable transmembrane domain (PubMed:21746876). Also associates with the actin cytoskeleton and membrane rafts in activated T-cells (PubMed:18641330, PubMed:10713127). A minor pool is associated with the plasma membrane and is enriched at the immunological synapse in activated T-cells (PubMed:22623988).
Diseases
- Malignant Neoplasms
- Neoplasms
- Malignant Squamous Cell Neoplasm
- Neoplasm Metastasis
- Carcinoma
- Squamous Cell Carcinoma Of Esophagus
- Cell Transformation, Neoplastic
- Monoclonal Gammapathies
- Monoclonal Gammopathy Of Undetermined Significance
- Esophageal Neoplasms
- Endometrial Polyp
- Multiple Myeloma
Pathways
- Cell Growth
- Cell Adhesion
- Pathogenesis
- Transport
- Cell Activation
- T Cell Activation
- Cell Cycle
- S Phase
- Hyperphosphorylation
- Cell Migration
- Electron Transport
- Proteolysis
- Transcytosis
PTMs
- Cleavage
Research Areas
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/STOML2
bosterbio.com/bosterbio-gene-info-cards/STOML2
References
PMID: 10713127 by Wang Y., et al. Identification and characterization of human SLP-2, a novel homologue of stomatin (band 7.2b) present in erythrocytes and other tissues.
PMID: 11435687 by Owczarek C.M., et al. A novel member of the stomatin/EPB72/mec-2 family, stomatin-like 2 (STOML2), is ubiquitously expressed and localizes to HSA chromosome 9p13.1.