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- Table of Contents
SUB1 Antibodies
AND SUB1 ELISA kits, SUB1 Proteins
Many biological assays use antibodies to detect SUB1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SUB1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SUB1 antibodies...
Designing a Western blot for SUB1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SUB1 Western Blot GuideDesigning an IHC experiment for SUB1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SUB1 IHC GuideSUB1 Infographic by Boster Bio
All SUB1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$370
Cat # M02698-3
100 μg/vial
Cat # M02698-3
100 μg/vial
Human, Mouse, Rat
IHC, WB
$370
Cat # M02698-2
100 μg/vial
Cat # M02698-2
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC, WB
$370
Cat # A02698-1
100 μg/vial
Cat # A02698-1
100 μg/vial
Human
Flow Cytometry, WB
$370
Cat # M02698-1
100 μg/vial
Cat # M02698-1
100 μg/vial
SUB1 Overview
Facts about Activated RNA polymerase II transcriptional coactivator p15.
Activated RNA polymerase II transcriptional coactivator p15 (SUB1)
General coactivator that works cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex.
Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
Gene Information
| Human | |
|---|---|
| Gene Name: | SUB1 |
| Uniprot: | P53999 |
| Entrez: | 10923 |
Family
| Belongs to: |
|---|
| transcriptional coactivator PC4 family |
Alternative Names
activated RNA polymerase II transcription cofactor 4; activated RNA polymerase II transcriptional coactivator p15; MGC102747; p15; PC4p14P15; Positive cofactor 4; RPO2TC1; SUB1 homolog (S. cerevisiae); SUB1 homolog
Molecular Weight
Mass (kDA):
14.395 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5p13.3 |
| Sequence: | 5; NC_000005.10 (32531778..32604079) |
Subcellular Localizations
Nucleus.
Diseases
- Cell Invasion
- Neoplasms
- Malignant Neoplasms
- Malaria
- Submersion
- Carcinoma
- Tissue Adhesions
- Hypoxia
- Malaria, Falciparum
- Tumor Angiogenesis
- Mammary Neoplasms
- Pathologic Neovascularization
Pathways
- Dna Repair
- Secretion
- Virulence
- Cell Cycle
- Chromatin Organization
- Proteolysis
- Cell Cycle Arrest
- Fermentation
- Localization
- Angiogenesis
- Pathogenesis
- Cell Adhesion
- Heterochromatin Organization
PTMs
- Phosphorylation
- Cleavage
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SUB1
bosterbio.com/bosterbio-gene-info-cards/SUB1
References
PMID: 8062392 by Kretzschmar M., et al. A novel mediator of class II gene transcription with homology to viral immediate-early transcriptional regulators.
PMID: 8062391 by Ge H., et al. Purification, cloning, and characterization of a human coactivator, PC4, that mediates transcriptional activation of class II genes.