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- Table of Contents
Facts about Spindlin-1.
Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006).
| Human | |
|---|---|
| Gene Name: | SPIN1 |
| Uniprot: | Q9Y657 |
| Entrez: | 10927 |

| Belongs to: |
|---|
| SPIN/STSY family |

OCR; spindlin 1; spindlin; spindlin-1; SPINOvarian cancer-related protein
Mass (kDA):
29.601 kDA

| Human | |
|---|---|
| Location: | 9q22.1 |
| Sequence: | 9; NC_000009.12 (88388444..88478694) |
Highly expressed in ovarian cancer tissues.
Nucleus. Nucleus, nucleolus.





PMID: 16098913 by Gao Y., et al. Spindlin1, a novel nuclear protein with a role in the transformation of NIH3T3 cells.
PMID: 21960006 by Wang W., et al. Nucleolar protein Spindlin1 recognizes H3K4 methylation and stimulates the expression of rRNA genes.