SUMF2 Antibodies

AND SUMF2 ELISA kits, SUMF2 Proteins

Many biological assays use antibodies to detect SUMF2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SUMF2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SUMF2 antibodies...

We validate the specificity of these antibodies to SUMF2 by testing them on tissues known to express SUMF2 positively and negatively. Browse below to find the SUMF2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for SUMF2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SUMF2 IHC Guide

SUMF2 Infographic by Boster Bio

All SUMF2 Products

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Product

Figures

Specificity

Applications

Price

Anti-SUMF2 Antibody Picoband®

Western blot analysis of SUMF2 using anti-SUMF2 antibody (A08890)

IHC analysis of SUMF2 using anti-SUMF2 antibody (A08890)

Human

ELISA, Flow Cytometry, IF, IHC, WB

$370
Cat # A08890
100 µg/vial

SUMF2 (NM_001042468) Human Over-expression Lysate

SUMF2 Human Over-expression Lysates NM_001042468

Human

$628
Cat # LS025870
20 µg, 100 µg

SUMF2 Overview

Facts about Inactive C-alpha-formylglycine-generating enzyme 2.

SUMF2 3D structure. Source: alphafold

Inactive C-alpha-formylglycine-generating enzyme 2 (SUMF2)

Lacks formylglycine generating activity and is unable to convert newly synthesized inactive sulfatases for their active form. Inhibits the activation of sulfatases by SUMF1.

Gene Information

Human
Gene Name:	SUMF2
Uniprot:	Q8NBJ7
Entrez:	25870

Family

Belongs to:

sulfatase-modifying factor family

Alternative Names

C-alpha-formyglycine-generating enzyme 2; C-alpha-formylglycine-generating enzyme 2; DKFZp566I1024; DKFZp686I1024; DKFZp686L17160; DKFZp781L1035; FGE2; MGC99485; paralog of the formylglycine-generating enzyme; pFGE; sulfatase modifying factor 2; sulfatase-modifying factor 2; SUMF2

Molecular Weight

Mass (kDA):
33.843 kDA

Genomic Context


Human

Location:	7p11.2
Sequence:	7; NC_000007.14 (56064007..56080672)

Tissue Specificity

Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highest levels in kidney, liver and placenta.

Subcellular Localizations

Endoplasmic reticulum lumen.

Diseases

Multiple Sulfatase Deficiency Disease
Deficiency Of Sulfatase
Lysosomal Storage Diseases
Sphingolipidoses
Crohn Disease
Inflammation
Noma

Storage Disease

Pathways

Secretion
Mrna Transcription
Glycosylation
Interleukin-13 Secretion
Localization

PTMs

Oxidation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SUMF2

References

PMID: 12757706 by Cosma M.P., et al. The multiple sulfatase deficiency gene encodes an essential and limiting factor for the activity of sulfatases.

PMID: 15708861 by Mariappan M., et al. Expression, localization, structural, and functional characterization of pFGE, the paralog of the Calpha-formylglycine-generating enzyme.