SUMO1P1 Antibodies

AND SUMO1P1 ELISA kits, SUMO1P1 Proteins

Many biological assays use antibodies to detect SUMO1P1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SUMO1P1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SUMO1P1 antibodies...

We validate the specificity of these antibodies to SUMO1P1 by testing them on tissues known to express SUMO1P1 positively and negatively. Browse below to find the SUMO1P1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SUMO1P1 Infographic by Boster Bio

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Anti-SUMO SUMO1P1 Antibody

Most modifiers mature by proteolytic processing from inactive precursors (a; amino acid)

Human

ELISA, WB

$711
Cat # A19764
500ug

SUMO1P1 Overview

Facts about Small ubiquitin-related modifier 5.

SUMO1P1 3D structure. Source: alphafold

Small ubiquitin-related modifier 5 (SUMO1P1)

Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Regulates the entire life cycle of promyelocytic leukemia nuclear bodies (PML-NBs).

PolySUMO1P1/SUMO5 conjugation on'Lys-160' of PML facilitates recruitment of PML-NB components, which enlarges PML-NB. SUMO1P1/SUMO5 also increases polySUMO2/3 conjugation of PML, leading to RNF4-mediated disruption of PML-NBs.

Gene Information

Human
Gene Name:	SUMO1P1
Uniprot:	G2XKQ0
Entrez:	391257

Family

Belongs to:

ubiquitin family

Alternative Names

Small ubiquitin-related modifier 5

Molecular Weight

Mass (kDA):
11.526 kDA

Genomic Context


Human

Location:	20q13.2
Sequence:	20; NC_000020.11 (53874498..53875709, complement)

Tissue Specificity

High expression levels in testes and peripheral blood leukocyte (PubMed:27211601). Expressed also in lung, placenta, liver, spleen and thymus (PubMed:27211601).

Subcellular Localizations

Nucleus. Forms prominent non-membrane-bound structures in the nucleus.

Interacting Proteins

AXIN1
C18orf25
CKS1B
EDARADD
ESRRG

FAM118B
FAM200A
FKBP6
HNRNPC
KRTAP9-2

L3MBTL3
LCE2A
LCE2D
MAPK1IP1L
NAB2

PIAS2
SATB1
SETBP1
SOX5
SSSCA1

STX1A
SUMO1
TRAF2
TRIM23
UBA2

UBE2I
ZBTB26
ZBTB6

PTMs

Isopeptide bond

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SUMO1P1

References

PMID: 27211601 by Liang Y.C., et al. SUMO5, a novel poly-sumo isoform, regulates pml nuclear bodies.

PMID: 30675988 by Albert L., et al. Modulating protein-protein interactions with visible-light responsive peptide backbone photoswitches.