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- Table of Contents
Facts about Sushi domain-containing protein 2.
May play a role in breast tumorigenesis (PubMed:23131994). .
| Human | |
|---|---|
| Gene Name: | SUSD2 |
| Uniprot: | Q9UGT4 |
| Entrez: | 56241 |

| Belongs to: |
|---|
| No superfamily |

BK65A6.2; FLJ22778; SUSD2; Sushi domain (SCR repeat) containing; sushi domain containing 2; sushi domain-containing protein 2
Mass (kDA):
90.208 kDA

| Human | |
|---|---|
| Location: | 22q11.23 |
| Sequence: | 22; NC_000022.11 (24181487..24189106) |
Highly expressed in breast cancer, but shows a restricted expression pattern in normal tissues such as adipose, adrenal gland, kidney, lung, mammary gland, placenta, thyroid, trachea, and uterus (PubMed:23131994). Also expressed in colon; down-regulated in colon cancer tissues (PubMed:25351403).
Cell membrane; Single-pass type I membrane protein. SUSD2 and LGALS1 co-localized in very specific, punctate regions along the cell membrane of breast cancer cells.





PMID: 23131994 by Watson A.P., et al. Multiple functions of sushi domain containing 2 (SUSD2) in breast tumorigenesis.
PMID: 25351403 by Pan W., et al. CSBF/C10orf99, a novel potential cytokine, inhibits colon cancer cell growth through inducing G1 arrest.